Articles
2024
Preprint
Sumire Ishida-Ishihara, Kan Yaguchi, Kimino Sato, Koya Yoshizawa, Sena Miura, Guang Yang, Krisztina Veszelyi, Gabor Banhegyi, Eva Margittai, and
Fragility of ER homeostatic regulation underlies haploid instability in human somatic cells
BioRχiv (2024) Link
Haploidy-linked cell proliferation defects limit larval growth in Zebrafish
BioRχiv (2024)Link
2023
Research Article
Takahiro Yamamoto, and
Cell shape instability during cytokinesis in tetraploid HCT116 cells
Biochemical and Biophysical Research Communications (2023) In press
, , , , Fuyu Sato, , , , , , , , Yasuhito Shimada, , and
Tetraploidy-linked sensitization to CENP-E inhibition in human cells
Molecular Oncology (2023)17: 1148-1166
2022
Research Article
Tomoko Kamasaki, Ryota Uehara, Yasuyuki Fujita
Ultrastructural Characteristics of Finger-Like Membrane Protrusions in Cell Competition
Microscopy (2022) in press
Takafumi Kamada, Kohei Otomo, Takashi Murata, Kaito Nakata, Shota Hiruma, Ryota Uehara, Mitsuyasu Hasebe, Tomomi Nemoto
Low-invasive 5D visualization of mitotic progression by two-photon excitation spinning-disk confocal microscopy
Scientific Reports (2022) 12, 809
2021
Research Article
Kosuke Nagata, Ken-ichi Bajo, Hideyuki Mitomo, Ryosuke Fujita, Ryota Uehara, Kuniharu Ijiro, Hisayoshi Yurimoto
Visualization of DNA replication in single chromosome by stable isotope labeling
Cell Structure and Function (2021) 46:95-101
Tomoko Kamasaki, Yumi Miyazaki, Susumu Ishikawa, Kazuya Hoshiba, Keisuke, Kuromiya, Nobuyuki Tanimura, Yusuke Mori, Motosuke Tsutsumi, Tomomi Nemoto, Ryota Uehara, Shiro Suetsugu, Toshiki Itoh, and Yasuyuki Fujita
FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells
iScience (2021) 24:102994
Guang Yang, Shota Hiruma, Akira Kitamura, Masataka Kinjo, Mithilesh Mishra, and Ryota Uehara* (*corresponding author)
Molecular basis of functional exchangeability between ezrin and other actin-membrane associated proteins during cytokinesis
Experimental Cell Research (2021) 403(2):112600
Kan Yaguchi, Kimino Sato, Koya Yoshizawa, Daisuke Mikami, Kohei Yuyama, Yasuyuki Igarashi, Gabor Banhegyi, Eva Margittai, and Ryota Uehara* (*corresponding author)
Mevalonate pathway-mediated ER homeostasis is required for haploid stability in human somatic cells
Cell Structure and Function (2021) 46:1-9
2020
Research Article
Koya Yoshizawa, Kan Yaguchi, and Ryota Uehara* (*corresponding author)
Uncoupling of DNA replication and centrosome duplication cycles is a primary cause of haploid instability in mammalian somatic cells
Frontiers in Cell and Developmental Biology (2020) 8:721 https://doi.org/10.3389/fcell.2020.00721
Noushaba Mafy, Kazuya Matsuo, Shota Hiruma, Ryota Uehara*, and Nobuyuki Tamaoki* (*co-corresponding author)
Photoswitchable CENP-E inhibitor enabling the dynamic control of chromosome movement and mitotic progression
Journal of the American Chemical Society (2020)142:1763-1767 Full Text
DOI: 10.1021/jacs.9b12782
2018
Research Article
Yaguchi, K., Yamamoto, T., Matsui, R., Shimada, M., Shibanuma, A., Kamimura, K., Koda, T., and Uehara, R.* (*corresponding author)
Tetraploidy-Associated Centrosome Overduplication in Mouse Early Embryos
Communicative & Integrative Biology (2018) e1526605-1-e1526605-4 [Full text (via HUSCAP)]
Yaguchi, K., Yamamoto, T., Shimada, M., Sugimoto, R., Nakamura, K., Ayabe, T., and Uehara, R.
Ploidy-dependent change in cyclin D2 expression and sensitization to cdk4/6 inhibition in human somatic haploid cells
Biochemical and Biophysical Research Communications (2018) 504(1):231-237 [Journal site]
, , , , , A., , K., , T., and
Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals
Journal of Cell Biology (2018) 217: 2463-2483 [Journal site] [Press release][Full text (via HUSCAP)]
2017
Research Article
Hiruma, S., Kamasaki, T., Otomo, K., Nemoto, T., and Uehara, R.* (*corresponding author)
Dynamics and function of ERM proteins during cytokinesis in human cells
FEBS Letters 591: 3296-3309(2017) Full text
Preprint
, , , , , , , and
Uncoordinated centrosome duplication cycle underlies the instability of non-diploid states in mammalian somatic cells
BioRχiv doi: https://doi.org/10.1101/194746
2016
Research Article
Uehara, R.*, Kamasaki, T., Hiruma, S., Poser, I., Yoda, K., Yajima, J., Gerlich, D.W., and Goshima, G. (*corresponding author)
Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission.
Molecular Biology of the Cell 1; 27; 812-827 (2016)
2015 以前
Research Article
Uehara, R.*, Tsukada, Y., Kamasaki, T., Poser, I., Yoda, K., Gerlich, D.W., and Goshima, G.* (*co-corresponding authors)
Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase.
Journal of Cell Biology 202:623-636 (2013) (Article)
Nakaoka, Y., Miki, T., Fujioka, R., Uehara, R., Tomioka, A., Obuse, C., Kubo, M., Hiwatashi, Y., and Goshima, G.
An inducible RNAi system in Physcomitrella patens reveals a dominant role of augmin in phragmoplast microtubule generation.
Plant Cell 24:1478-1493 (2012)
Uehara, R. and Goshima, G.
Functional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase.
Journal of Cell Biology 191: 259-267 (2010)
Uehara, R., Goshima, G., Mabuchi, I., Vale, R.D., Spudich, J. A., Griffis, E. R.
Determinants of myosin II cortical localization during cytokinesis.
Current Biology 20: 1080-1085 (2010)
Uehara, R., Nozawa, R., Tomioka, A., Petry, S., Vale, R., Obuse, C., and Goshima, G.
The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.
Proc Natl Acad Sci USA 106: 6998-7003 (2009)
Uehara, R., Hosoya, H., and Mabuchi, I.
In vivo phosphorylation of regulatory light chain of myosin II in sea urchin eggs and its role in controlling myosin localization and function during cytokinesis.
Cell Motility and Cytoskelton 65: 100-115 (2008)