論文

  1. S. Ishihara and H. Haga:
    “Matrix stiffness contributes to cancer progression by regulating transcription factors”
    Cancers, 14(4):1049 (2022).
  2. H. Oyama, A. Nukuda, S. Ishihara, H. Haga:
    “Soft surfaces promote astrocytic differentiation of mouse embryonic neural stem cells via dephosphorylation of MRLC in the absence of serum”
    Scientific Reports, 11(1):19574 (2021).
  3. S. Ishida-Ishihara, M. Akiyama, K. Furusawa, I. Naguro, H. Ryuno, T. Sushida, S. Ishihara, H. Haga:
    “Osmotic Gradient Induces Stable Dome Morphogenesis on Extracellular Matrix”
    Journal of Cell Science, 133, jcs243865 (2020).
  4. M. Frauenlob, D. R. King, H. Guo, S. Ishihara, M. Tsuda, T. Kurokawa, H. Haga, S. Tanaka, J. P. Gong:
    “Modulation and characterization of the double network hydrogel”
    Macromolecules, 52, 6704-6713 (2019).
  5. Y. Mizutani, H. Kobayashi, T. Iida, N. Asai, A. Masamune, A. Hara, N. Esaki, K. Ushida, S. Mii, Y. Shiraki, K. Ando, L. Weng, S. Ishihara, S. M. Ponik, M. W. Conklin, H. Haga, A. Nagasaka, T. Miyata, M. Matsuyama, T. Kobayashi, T. Fujii, S. Yamada, J. Yamaguchi, T. Wang, S. L. Woods, D. Worthley, T. Shimamura, M. Fujishiro, Y. Hirooka, M. Takahashi, A. Enomoto:
    “Meflin-positive cancer-associated fibroblasts inhibit pancreatic carcinogenesis”
    Cancer Research, 79, 5367-5381 (2019).
  6. Y. Kumagai, J. Nio-Kobayashi, S. Ishida-Ishihara, H. Tachibana, R. Omori, A. Enomoto, S. Ishihara, and H. Haga:
    “The intercellular expression of type-XVII collagen, laminin-332, and integrin-β1 promote contact following during the collective invasion of a cancer cell population”
    Biochemical and Biophysical Research Communications, 514, 1115-1121 (2019).
  7. K. Yamamoto, K. Otomo, T. Nemoto, S. Ishihara, H. Haga, A. Nagasaki, Y. Murakami, M. Takahashi:
    “Differential contributions of nonmuscle myosin IIA and IIB to cytokinesis in human immortalized fibroblasts”
    Experimental Cell Research, 376, 67-76 (2019).
  8. S. Ishihara, K. Aoki, T. Mizutani, M. Amano, S-I. Nishimura, H. Haga:
    “Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells”
    Cell Structure and Function, 43, 177-185 (2018).
  9. S. Ishihara, S. M. Ponik, and H. Haga:
    “Mesenchymal Stem Cells in Breast Cancer: Response to Chemical and Mechanical Stimuli”
    Oncoscience, 4, 158-159 (2017).
  10. S. Ishihara, D. R. Inman, W.J. Li, S. M. Ponik, and P. J. Keely:
    “Mechano-signal transduction in mesenchymal stem cells induces prosaposin secretion to drive the proliferation of breast cancer cells”
    Cancer Research, 77, 6179-6189 (2017).
  11. S. Ishihara, T. Mizutani, K. Kawabata, and H. Haga:
    “An improved method for western blotting when extracting proteins from mammalian cells cultured on a collagen gel under serum-free conditions”
    Cytotechnology, 68, 25-32 (2016).
  12. A. Nukuda, C. Sasaki, S. Ishihara, T. Mizutani, K. Nakamura, T. Ayabe, K. Kawabata, and H. Haga:
    “Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression”
    Oncogenesis, 4, e165 (2015).
  13. Y. Iguchi, S. Ishihara, Y. Uchida, K. Tajima, T. Mizutani, K. Kawabata, and H. Haga:
    “Filamin B enhances the invasiveness of cancer cells into 3D collagen matrices”
    Cell Structure and Function, 40, 61-67 (2015).
  14. K. Takemoto, S. Ishihara, T. Mizutani, K. Kawabata, and H. Haga:
    “Compressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway”
    PLOS ONE, 10, e0117937 (2015).
  15. S. Ishihara and H. Haga:
    “ATF5: development of oncogenic resistance to radiotherapy”
    Aging (Albany NY), 7, 453-454, (2015).
  16. S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, and H. Haga:
    “Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells”
    Oncotarget, 6, 4602-4614 (2015).
  17. H. Masuda, S. Ishihara, I. Harada, T. Mizutani, M. Ishikawa, K. Kawabata, and H. Haga:
    “Coating extracellular matrix proteins on a (3-aminopropyl)triethoxysilane-treated glass substrate for improved cell culture”
    BioTechniques, 56, 172-179 (2014).
  18. S. Ishihara, M. Yasuda, I. Harada, T. Mizutani, K. Kawabata, and H. Haga:
    “Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions”
    Experimental Cell Research, 319, 2916-2927 (2013).
  19. X. Li, S. Ishihara, M. Yasuda, T. Nishioka, T. Mizutani, M. Ishikawa, K. Kawabata, H. Shirato, and H. Haga:
    “Lung cancer cells that survive ionizing radiation show increased integrin α2β1- and EGFR-dependent invasiveness”
    PLOS ONE, 8(8): e70905 (2013).
  20. S. Ishihara, M. Yasuda, T. Mizutani, K. Kawabata, H. Shirato, T. Nishioka and H. Haga:
    “Irradiation-tolerant lung cancer cells acquire invasive ability dependent on dephosphorylation of the myosin regulatory light chain”
    FEBS Letters, 587, 732-736 (2013).
  21. S. Ishihara, H. Haga, M. Yasuda, T. Mizutani, K. Kawabata, H. Shirato and T. Nishioka:
    “Integrin β1-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix”
    Biochemical and Biophysical Research Communications, 396, 651-655 (2010).
  22. K. Tsutsumi, M. Tsuda, N. Yazawa, H. Nakamura, S. Ishihara, H. Haga, M. Yasuda, R. Yamazaki, H. Shirato, H. Kawaguchi, T. Nishioka, and Y. Ohba :
    “Increased motility and invasiveness of tumor cells that survived 10 Gy irradiation”
    Cell Structure and Function, 34, 89-96 (2009).