古澤 和也 FURUSAWA Kazuya　助教

• 北海道大学 大学院先端生命科学研究院（助教）
  古澤　和也　ふるさわ　かずや
  

経歴

• 昭和56年 群馬県前橋市広瀬町生まれ
• 平成12年 前橋市立前橋高等学校卒業
• 平成15年 群馬大学工学部生物化学工学科　大学院修士課程への飛び級進学のため中退
• 平成17年 群馬大学群馬大学院生物化学工学専攻　修了
• 平成20年 群馬大学大学院生産工学専攻　修了
• 平成20年 関西学院大学大学院理工学研究科　博士研究員
• 平成20年 北海道大学大学院先端生命科学研究院　組織構築科学研究室　助教
• 平成29年 北海道大学大学院先端生命科学研究院　細胞ダイナミクス科学研究室　助教

現在の研究分野

高分子物理学、生体材料学、組織工学

主な研究テーマ

• 生体高分子の自己組織化を利用した新規生体材料の創製

• 複雑な階層構造を持つ再生組織の構築

• 再生組織の形態形成レオロジー

所属学会

高分子学会、日本物理学会、日本バイオレオロジー学会、日本Material Research Society （日本MRS）、日本再生医療学会、アメリカ化学会

担当講義

• 生体高分子の物理化学Ⅱ
• 生体高分子学基礎実験
• 生体高分子学実験Ⅰ
• 生物系の反応速度論
• 自主研究Ⅱ

受賞

研究業績

2017年

• Y. Maki, K. Furusawa, T. Dobashi, Y. Sugimoto, K. Wakabayashi: Small-angle X-ray and light scattering analysis of multi-layered Curdlan gels prepared by a diffusion method, Carbohydrate Polymers, 155, 136-145 (2017).

2016年

• N. Sasaki, Y. Saitoh, R. K. Sharma, K. Furusawa: Determination of the elastic modulus of β-lactoglobulin amyloid fibrils by measuring the Debye-Waller factor, International Journal of Biological Macromolecules, 92, 240-245 (2016).
• T. Mizutani, K. Furusawa, H. Haga, K. Kawabata: Heterogeneous filament network formation by myosin light chain isoforms effects on contractile energy output of single cardiomyocytes derived from human induced pluripotent stem cells, Regenerative Therapy, 3, 90-96 (2016).
• K. Furusawa, T. Mizutani, N. Sasaki: Development of the evaluation system for barrier functions of engineered epithelial lumens, Regenerative Therapy, 3, 82-89 (2016).
• E. C. Ossai, Y. Tomimori, S. Ohki, K. Okada, T. Yonekura, K. Furusawa, N. Sasaki: Morphology and Properties of Globular Polymeric Materials in the Solid State: A Composite Material of DNA with a Cationic Surfactant, Journal of Polymer Science: part B: Polymer Physics, 54, 730-738 (2016).

2015年

• M. Imai, K. Furusawa, T. Mizutani, K. Kawabata, H. Haga: Three-dimensional morphogenesis of MDCK cells induced by cellular contractile forces on a viscous substrate, Scientific Reports, 5, 14208 (2015).
• K. Furusawa, T. Mizutani, H. Machino, S. Yahata, A. Fukui, N. Sasaki: Application of multichannel collagen gels in construction of epithelial lumen-like engineered tissues, ACS Biomaterials Science & Engineering 1, 539-548 (2015).

2014年

• Y. Maki, K. Furusawa, S. Yasuraoka, H. Okamura, N. Hosoya, M. Sunaga, T. Dobashi, Y. Sugimoto, K. Wakabayashi: Universality and specificity in molecular orientation in anisotropic gels prepared by diffusion method, Carbohydrate Polymers, 108, 118-126  (2014).
• R. K. Sharma, K. Furusawa, A. Fukui, N. Sasaki: Effect of a flow field on amyloid fibrillogenesis in a β-lactoglobulin solution, International Journal of Biological Macromolecules, 70, 490-497 (2014).

2013年

• Y. Hanazaki, S. Sato, J. Masumoto, K. Furusawa, A. Fukui, N. Sasaki: Multiscale Analysis of Changes in an Anisotropic Collagen Gel Structure by Culturing Osteoblasts, ACS Applied Materials and Interfaces, 5, 5937-5945 (2013).
• N. Sasaki, H. Shirakawa, T. Nozoe, K. Furusawa: Elastic Properties of Collagen in Bone Determined by Measuring the Deby-Waller Factor, Journal of Biomechanics, 46, 2824-2830 (2013).
• H. Shirakawa, K. Furusawa, A. Fukui, S. Tadano, N. Sasaki: Changes in the viscoelastic properties of cortical bone by selective degradation of matrix protein, Journal of Biomechanics, 46, 696-701 (2013).
• Y. Hanazaki, D. Ito, K. Furusawa, A. Fukui, N. Sasaki: Change in the viscoelastic properties of agarose gel by HAp precipitation by osteoblasts cultured in an agarose gel matrix, Journal of Biorheology (Published online: 22 November 2011), 26, 21-28 (2013).
• S. Mishra, T. Nagata, K. Furusawa, N. Sasaki, and A. Fukui: Expression of xSDF-1α, xCXCR4 and xCXCR7 during gastrulation in Xenopus laevis, International Journal of Developmental Biology, 2013, 57, 95-100 (2013).

2012年

• K. Furusawa, S. Sato, J. Masumoto, Y. Hanazaki, Y. Maki, T. Dobashi, T. Yamamoto, A. Fukui and N. Sasaki: Studies on the Formation Mechanism and the Structure of the Anisotropic Collagen Gel Prepared by Dialysis-Induced Anisotropic Gelation, Biomacromolecules, 13, 29-39 (2012). Corrections: Biomacromolecules, 13, 1232-1232 (2012).

2011年

• Y. Maki, K. Ito, N. Hosoya, C. Yoneyama, K. Furusawa, T. Yamamoto, T. Dobashi, Y. Sugimoto, K. Wakabayashi: Anisotropic structure of calcium-induced alginate gels by optical and small-angle X-ray scattering measurements, Biomacromolecules, 12(6), 2145-2152 (2011).
• K. Furusawa, H. Shirakawa, S. Sato, Y. Tomimori, B. Giri, A. Fukui, N. Sasaki: Wide angle X-ray diffraction and small angle X-ray scattering studies on the effect of demineralization on hierarchical structure of bone, Transactions of the Materials Research Society of Japan, 36, 387-391 (2011).

2010年

• K. Furusawa, Y. Narazaki, N. Tomita, T. Dobashi, N. Sasaki, T. Yamamoto: Effect of pH on anisotropic gelation of DNA induced by aluminum cations, The journal of physical chemistry. B, 114(44), 13923-13932 (2010).
• S. C. Lin, Y. Minamisawa, K. Furusawa, Y. Maki, H. Takeno, T. Yamamoto, T. Dobashi: Phase relationship and dynamics of anisotropic gelation of carboxymethylcellulose aqueous solution, Colloid and polymer science, 288, 695-701 (2010).

 2009年

• K. Furusawa, Y. Minamisawa, T. Yamamoto, T. Dobashi: Aluminum ion-induced anisotropic gelation of DNA, Soft Materials, 7, 132-149 (2009).

 2008年

• K. Furusawa, E. Kita, T. Saheki, N. Nagasawa, N. Nishi, T. Dobashi: Carcinogen adsorbent prepared from DNA complex by gamma-ray irradiation, Journal of biomaterials science, Polymer edition, 19, 1159-1170 (2008).

 2007年

• K. Furusawa, Y. Minamisawa, T. Dobashi, T. Yamamoto: Dynamics of liquid crystalline gelation of DNA, The journal of physical chemistry. B, 111(51), 14423-14430 (2007).
• K. Furusawa, M. Wakamatsu, T. Dobashi, T. Yamamoto: Adsorption kinetics of carcinogens to DNA liquid crystalline gel beads, Langmuir: the ACS journal of surfaces and colloids, 23(20), 10081-10087 (2007).
• T. Dobashi, K. Furusawa, E. Kita, Y. Minamisawa, T. Yamamoto: DNA liquid-crystalline gel as adsorbent of carcinogenic agent, Langmuir: the ACS journal of surfaces and colloids, 23(3), 1303-1306 (2007).

 2006年

• Y. Umino, S. Morishita, R. Kita, N. Shinyashiki, S. Yagihara, K. Furusawa, T. Dobashi, N. Nagasawa: Water and chain dynamics in polymer network structure, Transactions of the Materials Research Society of Japan, 31, 767-770 (2006).
• Y. Minamisawa, K. Furusawa, T. Yamamoto, T. Dobashi: Mono- and Multilayered Aluminum ion-induced liquid crystalline gel of DNA, Transactions of the Materials Research Society of Japan, 31, 739-741 (2006).

2005年

• K. Furusawa, K. Terao, N. Nagasawa, F. Yoshii, K. Kubota, T. Dobashi: Nanometer-sized gelatin particles prepared by means of gamma-ray irradiation, Colloid and polymer science, 283, 229-233 (2005).
• K. Furusawa, T. Dobashi, S. Morishita, M. Oyama, T. Hashimoto, N. Shinyashiki, S. Yagihara, N. Nagasawa: Structural and kinetic modification of aqueous hydroxypropylmethylcellulose (HPMC) induced by electron beam irradiation, Physica A, 353, 9-20 (2005).

2003年

• K. Terao, N. Nagasawa, H. Nishida, K. Furusawa, Y. Mori, F. Yoshii, T. Dobashi: Reagent-free crosslinking of aqueous gelatin: manufacture and characteristics of gelatin gels irradiated with gamma-ray and electron beam, Journal of biomaterials science, Polymer edition, 14, 1197-1208 (2003).