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Yokoi Y., Nishimura S-I., “Effect of Site‐specific O-Glycosylation on the Structural Behavior of NOTCH1 Receptor Extracellular EGF‐like Domains 11 and 10”, Chem. Eur. J.  26, 12363-12372 (2020)

Hayakawa S., Matsushita T., Yokoi Y., Wakui H., Garcia-Martin F., Hinou H., Matsuoka K., Nouso K., Kamiyama T., Taketomi A and Nishimura S-I., “Impaired O‑Glycosylation at Consecutive Threonine TTX Motifs in Mucins Generates Conformationally Restricted Cancer Neoepitopes”, Biochemistry 59, 1221-1241 (2020)

Sato R., Tsuchiya K., Matsuzaki H., Takei N., Itoh H., Kanayama N., Suda T., Watanabe H., Ohashi T., Tanaka M., Nishimura S-I and Maekawa M., “Fetal environment and glycosylation status in neonatal cord blood: a comprehensive mass spectrometry-based glycosylation analysis”, Medicine 94, e3219 (2016)

Inafuku S., Noda K., Amano M., Nishimura S-I and Ishida S., “Increase of Sialylated N-glycans in Eyes with Neovascular　Glaucoma Secondary to Proliferative Diabetic Retinopathy”, Curr. Eye Res. 41, 721-724 (2016)

Kitatsuji C., Izumi K., Nambu S., Kurogochi M., Uchida T., Nishimura S-I., Iwai K., Mark R. O’Brian, Ikeda-Saito M and Ishimori K., “Protein oxidation mediated by heme-induced active site conversion specific for heme-regulated transcription factor, iron response regulator”, Sci. Rep. 6, 18703 (2016)

Udono M., Fujii K., Harada G., Tsuzuki Y., Kadooka K., Zhang P., Fujii H., Amano M.,  Nishimura S-I., Tashiro K., Kuhara S and Katakura Y., “Impaired ATP6V0A2 expression contributes to Golgi dispersion and glycosylation changes in senescent cells”, Sci. Rep. 5, 17342 (2015)

Akimoto Y., Nouso K., Kato H., Miyahara K.,  Dohi C., Morimoto Y., Kinugasa H., Tomoda T., Yamamoto N., Tsutsumi K., Kuwaki K., Onishi H., Ikeda F., Nakamura S., Shiraha H.,  Takaki A., Okada H., Amano M., Nishimura S-I and Yamamoto K. “Serum N-glycan profiles in patients with intraductal papillary mucinous neoplasms of the pancreas”, Pancreatology 15, 432-438 (2015)

322

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320

Ishida J., Hinou H., Naruchi K and Nishimura S-I., “Synthesis of neoglycosphingolipid from nethoxyamino-functionalized ceramide”, Bioorg. Med. Chem. Lett. 24, 1197-1200 (2014)

Hatakeyama S., Amano M., Tobisawa Y., Yoneyama T., Tsuchiya N., Habuchi T., Nishimura S-I and Ohyama C., “Serum N-glycan alteration associated with renal cell carcinoma detected by high-throughput glycan analysis”, J. Urol. 191, 805-813 (2014)

318

Matsushita T., Takada W., Igarashi K., Naruchi K., Miyoshi R., Garcia-Martin F.,  Amano M., Hinou H and Nishimura S-I., “A straightforward protocol for the preparation of high performance microarray displaying synthetic MUC1 glycopeptides”, BBA-GenSubjects 1840, 1105-1116 (2014)

317

Ishihara T., Kakiya K., Takahashi K., Miwa H., Rokushima M., Yoshinaga T., Tanaka T., Togame T., Takemoto H., Amano M., Iwasaki N.,Minami A and Nishimura S-I., “Discovery of novel differentiation markers in the early stage of chondrogenesis by glycoform-focused reverse proteomics and genomics”, BBA-GenSubjects 1840, 645-655 (2014)

316

Miyahara K., Nouso K., Miyake Y., Nakamura S., Obi S., Amano M., Hirose K., Nishimura S-I and Yamamoto K., “Serum glycan as a prognostic marker in patients with advanced hepatocellular carcinoma treated with sorafenib”, Hepatology 59, 355-356 (2014)

315

Nakagawa S., Shimamura S., Takaki Y., Suzuki Y.,  Murakami S., Watanabe T., Fujiyoshi S., Mino S.,  Sawabe T., Maeda T., Makita H., Nemoto S.,  Nishimura S-I., Watanabe H., Watsuji T andTakai K, “Allying with armored snails: the complete genome of gammaproteobacterialendosymbiont.”, ISME J. 8, 40-51 (2014)

313

Takeuchi M., Amano M., Kitamura H., Tsukamoto T., Masumori N., Hirose K., Ohashi T and Nishimura S-I., “N- and O-glycome analysis of serum and urine from bladder cancer patients using a high-throughput glycoblotting method”, Journal of Glycomics & Lipidomics 3, 108 (2013)

312

Kumar R., Naruchi K., Miyoshi R., Hinou H and Nishimura S-I., “A New Approach for the Synthesis of Hyper-Branched N-Glycan Core Structures from Locust Bean Gum”, Org. Lett. 15, 6278-6281 (2013)

311

Miyahara K., Nouso K., Saito S., Hiraoka S., Harada K., Takahashi S., Morimoto Y., Kobayashi S., Ikeda F., Miyake Y., Shiraha H., Takaki A., Amano M., Nishimura S.-I, Yamamoto K., “Serum glycan markers for evaluation of disease activity and prediction of clinical course in patients with ulcerative colitis. ”, PLOS ONE  8, e74861 (2013)

310

Hideshima S., Hinou H., Ebihara D., Sato R., Kuroiwa S., Nakanishi T., Nishimura S-I., Osaka T., “Attomolar Detection of Influenza A Virus Hemagglutinin Human H1 and Avian H5 Using Glycan-blotted Field Effect Transistor Biosensor”, Anal. Chem. 85, 5641-5644 (2013)

309

Feng F., Sakoda Y., Ohyanagi T., Nagahori N., Shibuya H., Okamastu M., Miura N., Kida H., Nishimura S-I., “Novel thiosialosides tethered to metal nanoparticles as potent influenza A virus hemagglutinin blockers”, Antivir. Chem. Chemoth. 23, 59-65 (2013)

308

Nouso K., Amano M., Miyahara K., Ito M. Y., Miyahara K., Morimoto Y., Kato H., Tsutsumi K., Tomoda T., Yamamoto N., Nakamura S., Kobayashi S., Kuwaki K., Hagihara H., Onishi H., Miyake Y., Ikeda F., Shiraha H., Takaki A., Nakahara T., Nishimura S-I., Yamamoto K., “Clinical utility of high-throughput glycome analysis in patients with pancreatic cancer”, J. Gastroenterology 48, 1171-1179 (2013)

307

Matsushita T., Ohyabu N., Fujitani N., Naruchi K., Shimizu H., Hinou H., Nishimura S-I.,  “Site-specific conformational alteration induced by sialylation of MUC1 tandem repeating glycopeptides at an epitope region for anti-KL-6 monoclonal antibody”, Biochemistry 52, 402-414 (2013)

306

305

Matsushita T., Handa S., Naruchi K., Garcia-Martin F., Hinou H., Nishimura S-I., “A novel approach for the parallel synthesis of glycopeptides by combining solid-phase peptide synthesis and dendrimer-supported enzymatic modifications”, Polym.J. 45, 854-862 (2013)

304

Izumi R., Matsushita T., Fujitani N., Naruchi K., Shimizu H., Tsuda S., Hinou H., Nishimura S-I., “Microwave-assisted solid-phase synthesis of antifreeze glycopeptides”, Chem. Eur. J. 19, 3913-3920 (2013)

303

Okamatsu M., Feng F., Ohyanagi T., Nagahori N., Someya K., Sakoda Y., Miura N., Nishimura S-I., Kida H.,“Fluorescence polarization-based assay using N-glycan-conjugated quantum dots for screening in hemagglutinin blockers for influenza A viruses”, J. Virol. Methods 187, 390-394 (2013)

302

Furukawa T., Arai M., Garcia-Martin F., Amano M., Hinou H., Nishimura S-I., “Glycoblotting-based high throughput protocol for the structural characterization of hyaluronan degradation products during enzymatic fragmentation”, Glycoconjugate J. 30, 171-182 (2013)

301

Kai H., Hinou H., Naruchi K., Matsushita T., Nishimura S-I., “Macrocyclic Mechanism-based Inhibitor for Neuraminidases”, Chem. Eur. J. 19, 1364-1372 (2013)

Nagahori N., Yamashita T., Amano M., Nishimura S-I.,“Effect of ganglioside GM3 synthase gene knockout on the glycoprotein N-glycan profile of mouse embryonic fibroblast”, ChemBioChem 14, 73-82 (2013)

299

Kimura K., Tanaka I., Nishimura S-I., Miyoshi R., Miyoshi T., Watanabe Y., “Further examination of polysaccharides causing membrane fouling in membrane bioreactors (MBRs): Application of lectin affinity chromatography and MALDI-TOF/MS”, Water Res. 46, 5725-5734 (2012)

298

Manri N., Takegawa Y., Fujitani N., Kaneko A., Hirabayashi A., Nishimura S-I., Sakamoto T., “Determination of O-Glycosylation Heterogeneity Using a Mass-Spectrometric Method Retaining Sugar Modifications”, Anal. Sci. 28, 723-727 (2012)

297

Amano M., Eriksson H, Manning J.C., Detjen K. M., André S., Nishimura S-I, Lehtiö J., and Gabius H.-J., “Tumor suppressor p16^INK4a: anoikis-favoring decrease in N/O-glycan/cell surface sialylation by downregulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model”, FEBS J.  279, 4062-4080 (2012) 

296

Furukawa T., Hinou H, Nishimura S-I.,“Strict Stereocontrol by 2,4-O-Di-tert-butylsilylene Group on β-Glucuronylations”, Org. Lett. 14, 2102-2105 (2012)

Kai H, Hinou H, Nishimura S-I., “Aglycone-focused randomization of 2-difluoromethylphenylsialoside-type suicide substrates for neuraminidases”, Bioorgan. Med. Chem. 20, 2739-2746 (2012)

294 

Nishimura S-I., Hato M., Hyugaji S., Feng F., and Amano M., “Glycomics for drug discovery: Metabolic perturbation in androgen-independent prostate cancer cells induced by unnatural hexosamine mimics”, Angew. Chem. Int. Ed. 51, 3386-3390 (2012)

293 

Hoshi H., Shimawaki K., Takegawa Y., Ohyanagi T., Amano M., Hinou H., and Nishimura S-I., “Molecular shuttle between extracellular and cytoplasmic space allows for monitoring of GAG biosynthesis in human articularchondrocytes”, Biochim. Biophys. Acta 1820, 1391-1398 (2012) 

292 

Garcia-Martin F., Hinou H., Matsushita T., Hayakawa S., and Nishimura S-I., “An efficient protocol for the solid-phase synthesis of glycopeptides under microwave irradiation”, Org. Biomol. Chem. 10, 1612-1617 (2012) 

291

Yoshimura Y., Aaron S. Nudelman., Steven B. Levery., Hans H. Wandall., Eric P. Bennett., Ole Hindsgaul., Henrik Clausen and Nishimura S-I.,“Elucidation of the sugar recognition ability of the lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 by using unnatural glycopeptide substrates”, Glycobiology 22, 429-438 (2012)

290 

Abe M., Shimaoka H., Fukushima M., and Nishimura S-I., “A cross-linked polymer possessing a high density of hydrazide groups: High-throughput glycan purification and labeling for high-performance liquid chromatography analysis”, Polym. J. 44, 269-277(2012) 

289 

Amano M., Hashimoto R., and Nishimura S-I., “Effects of single genetic damage in carbohydrate recognizing proteins on mouse serum N-glycan profile revealed by a simple glycotyping analysis”, ChemBioChem. 13, 451-464 (2012) 

288 

Takimori S., Shimaoka H., Furukawa J-i., Yamashita T., Amano M., Fujitani N., Takegawa Y., Hammarstrom L., Kacskovics I., Shinohara Y., and Nishimura S-I., “Alteration of the N-glycome of bovine milk glycoproteins during early lactation” , FEBS J. 278, 3769-3781 (2011) 

287 

Furukawa T., Hinou H., Shimawaki K., Nishimura S-I., “A potential glucuronateglycosyl donor with 2-O-acyl-6,3-lactone structure: efficient synthesis of glycosaminoglycan disaccharides”, TetrahedoronLett. 52, 5567-5570 (2011) 

286 

Hinou H., Saito N., Maeda T., Matsuda M., Kamiya Y., and Nishimura S-I., “Toward Green and Sustainable Chemical Glycosylation: Enhanced Lewis Acidity of Recyclable Solid Super Acid Catalyst, SO4/ZrO2 by CaC12 Dpoing”, J. Carbohyd. Chem. 30, 575-586 (2011) 

285 

Ohyanagi T., Nagahori N., Shimawaki K., Hinou H., Yamashita T., Sasaki A., Jin T., Iwanaga T., Kinjo M., and Nishimura S-I., “Importance of sialic acid residues illuminaterd by live animal imaging using phosphorylcholine self-assembled monolayers-coated quantum dots”, J. Am. Chem. Soc. 133, 12507-12517(2011) 

284 

Ishihara T., Fukuda I., Morita A., Takinami Y., Okamoto H., Nishimura S-I., and Numata Y., “Development of quantitative plasma N-glycoproteomics using label-free 2-D LC-MALDI MS and its applicability for biomarker discovery in hepatocellular carcinoma”, J. Proteomics 74, 2159-2168 (2011) 

283 

Urita A., Matsuhashi T., Onodera T., Nakagawa H., Hato M., Amano M., Seito N., Minami A., and Nishimura S-I., “Alterations of High-mannose Type N-Glycosylation in Human and Mouse Ostesarthritis Cartilage”, Arthritis & Rheumatism 63, 3428-3438 (2011) 

282 

Hirose K., Amano M., Hashimoto R., Yuan L and Nishimura S-I., “Insight into glycan diversity and evolutionary lineage based on comparative avio-N-glycomics and sialic acids analysis of 88 egg whites of Galloanserae”, Biochemistry 50, 4757-4774 (2011) 

281 

Hinou H., Miyoshi R., Takasu Y., Kai H., Kurogochi M., Arioka S., Gao X-D., Miura N., Fujitani N., Otomo S., Yoshinaga T., Fujiwara T., Noshi T., Togame H., Takemoto H., and Nishimura S-I., “A Strategy for Neuraminidase Inhibitors Using Mechanism-Based Labeling Information”, Chem. Asian J. 6, 1048-1056 (2011) 

280 

Naruchi K., and Nishimura S-I., “Membrane-Bound Stable Glycosyltransferases: Highly Oriented Protein Immobilization by a C-Terminal Cationic Amphipathic Peptide”, Angew. Chem. Int. Ed. 80, 1328-1331 (2011) 

279 

Hashimoto R., Fujitani N., Takegawa Y., Kurogochi M., Matsushita T., Naruchi K., Ohyabu N., Hinou H., Gao X-D., Manri N., Satake H., Kaneko A., Sakamoto T., and Nishimura S-I., “An efficient approach for the characterization of mucin type glycopeptides: The effect of O-glycosylation on the conformation of synthetic mucin peptides”, Chem. Eur. J. 17, 2393-2404 (2011) 

278 

Irie T., Majima T., Sawaguchi N., Funakoshi T., Nishimura S-I., and Minami A., “Biomechanical and histologic evaluation of tissue enjinnered ligaments using chitosan and hyaluronan hybrid polymer fibers: A rabbit medial collateral ligament reconstruction model”, J. Biomed. Mater. Res. Part A 97A, 111-117(2011) 

277 

Miura Y., Kato K., Takegawa Y., Kurogochi M., Furukawa J.-i., Shinohara Y., Nagahori N., Amano M., Hinou H., and Nishimura S-I., “Glycoblotting-assisted O- glycomics:Ammoniumcarbamate allows for highly efficient O-glycan release from glycoproteins”, Anal. Chem. 82, 10021-10029 (2010) 

276 

Matsushita T., Nagashima I., Fumoto M., Ohta T., Yamada K., Shimizu H., Hinou H., Naruchi K., Ito T., Kondo H., and Nishimura S-I., “Artificial Golgi apparatus: Globular protein-like dendrimer facilitates fully automated enzymatic glycan synthesis”, J. Am. Chem. Soc. 132, 16651-16656 (2010) 

275 

Ueda T., Ito T., Tomita K., Togame H., Fumoto M., Asakura K., Oshima T., Nishimura S-I., and Hanasaki K., “Identification of glycosylated exendin-4 analogue with prolonged blood glucose-lowering activity through glycosylation scanning substitution”, Bioorg. Med. Chem. Lett. 20, 4631-4634 (2010) 

274 

Shimizu H. K., Hosoguchi K., Liu Y., Fujitani N., Ohta T., Hinou H., Matsushita T., Shimizu H., Feizi T., and Nishimura S-I., “Chemical synthesis, folding and structural insights into O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor”, J. Am. Chem. Soc. 132, 14857-14865 (2010) 

Hosoguchi K., Maeda T., Furukawa J.-i., Shinohara Y., Hinou H., Sekiguchi M., Togame H., Takemoto H., Kondo H., and Nishimura S-I., “An Efficient Approach to the Discovery of Potent Inhibitors against Glycosyltransferases”, J. Med. Chem. 53, 5607-5619 (2010) 

272

Hashimoto R., Hirose K., Sato T., Fukushima N., Miura N., and Nishimura S-I., “Functional network of glycan-related molecules: Glyco-Net in Glycoconjugate Data Bank”, BMC. Syst. Biol. 4, 91 (2010)  

271 

Kurogochi M., Matsushita T., Amano M., Furukawa J.-i., Shinohara Y., Aoshima M., and Nishimura S-I., “Sialic acid-focused quantitative mouse serum glycoproteomics by multiple reaction monitoring assay”, Mol. Cell. Proteomics. 9, 2354-2368 (2010) 

270 

Yoshimura Y., Matsushita T., Fujitani N., Takegawa Y., Fujihira H., Naruchi K., Gao, X-D., Manri N., Sakamoto T., Kato K., Hinou H., and Nishimura S-I., “Unexpected Tolerance of Glycosylation by UDP-GalNAc:Polypeptide alpha-N-Acetylgalactosaminyltransferase Revealed by Electron Capture Dissociation Mass Spectrometry: Carbohydrate as Potential Protective Groups”, Biochemistry 49, 5929-5941 (2010) 

269 

Feng F., Miura N., Isoda N., Sakoda Y., Okamatsu M., Kida H., and Nishimura S-I., “Novel trivalent anti-influenza reagent”, Bioorg. Med. Chem. Lett. 20, 3772-3776 (2010) 

268 

Carvalho S., Sola-Penna M., Oliveira I., Pita S., Goncalves A., Neves B., Sousa F., Freire-de-Lima., Kurogochi M., Hinou H., Nishimura S-I., Previato J., and Todeschini A., “A new class of mechanism-based inhibitors for Trypanosamacruzi trans-sialidase and their influence on parasite virulence”, Glycobiology 20, 1034-1045 (2010) 

267 

Ito T, Sadamoto R., Naruchi K., Togame H., Takemoto H., Hondo H., and Nishimura S-I., “Highly Oriented Recombinant Glycosyltransferases: Site-Specific Immobilization of Unstable Membrane Proteins by using Staphylococcus aureusSortase A”, Biochemistry 49, 2604-2614 (2010) 

266 

Kimura A., Tandang M.-R., Fukuda T., Cabanos C., Takegawa Y., Amano M., Nishimura S-I., Matsumura Y., Maruyama N., and Utsumi S., “Carbohydrate moieties contribute significantly to the excellent physicochemical properties of French bean 7S globulin phaseolin”, J. Agric. Food. Chem. 58, 2923-2930 (2010) 

265 

Arioka S., Sakagami M., Uematsu R., Yamaguchi H., Togame H., Takemoto H., Hinou H., and Nishimura S-I., “Potent inhibitor scaffold against Trypanosomacruzi trans-sialidase”, Bioorgan. Med. Chem. 18, 1633-1640 (2010) 

264 

Amano M., Yamaguchi M., Takegawa Y., Yamashita T., Terasima M., Furukawa J.-i., Miura Y., Shinohara Y., Iwasaki N., Minami A., and Nishimura S-I., “Threshold in Stage Specific Embryonic Glycotypes Uncovered by a Full Portrait of Dynamic N-Glycan Expression during Cell Differentiation”, Mol. Cell. Proteomics. 9, 523-537 (2010) 

This publication list only displays the ones published after 2010.
2010年以降の論文を載せています。