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\"\"<\/p>\r\n

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\"\"<\/p>\r\n

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\u3000\u306f\u3044\u3001\u305d\u3046\u3067\u3059\u306d\u3002\u305d\u308c\u306f\u611f\u3058\u307e\u3059\u306d\u3002\u79c1\u3092\u6210\u9577\u3055\u305b\u3066\u3044\u305f\u3060\u3044\u305f\u306e\u306f\u3001\u9593\u9055\u3044\u306a\u304f\u3053\u306e\u7814\u7a76\u5ba4\u306e\u304a\u304b\u3052\u3060\u3068\u601d\u3046\u306e\u3067\u3001\u79c1\u306f\u305d\u3046\u601d\u3044\u307e\u3059\u3002\u3068\u3044\u3046\u306e\u3082\u751f\u304d\u7269\u7cfb\u3067\u3001\u79c1\u306f\u3044\u307e\u30dd\u30b9\u30c9\u30af\u307e\u3067\u3084\u3063\u3066\u308b\u306e\u30674\u5e74\u751f\u3068\u4fee\u58eb1\u30fb2\u5e74\u3001\u30c9\u30af\u30bf\u30fc3\u5e74\u306e\u3001\u5408\u8a087\uff5e8\u5e74\u306b\u306a\u308a\u307e\u3059\u304c\u3001\u751f\u304d\u7269\u7cfb\u306e\u8ad6\u6587\u306a\u3069\u304c\u30015\u30fb6\u672c\u3001\u51fa\u305b\u3066\u3044\u308b\u3093\u3067\u3059\u3088\u306d\u3002\u3053\u308c\u306b\u306f\u3059\u3054\u304f\u611f\u8b1d\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\r\n

\u3000\u3053\u306e\u7814\u7a76\u5ba4\u3067\u306f\u3001\u81ea\u5206\u3067\u8003\u3048\u3066\u3001\u81ea\u5206\u3067\u8ad6\u6587\u66f8\u3044\u3066\u3068\u306a\u308b\u306e\u3067\u3001\u3084\u3063\u3071\u308a\u7814\u7a76\u8005\u306f\u80b2\u3064\u3068\u601d\u3044\u307e\u3059\u306d\u3002\u8ad6\u6587\u3082\u51fa\u3055\u305b\u3066\u3082\u3089\u3063\u3066\u3044\u307e\u3059\u3057\u3001\u30b0\u30e9\u30f3\u30c8\u3001\u7814\u7a76\u4e88\u7b97\u3067\u3059\u306d\u3002\u3053\u308c\u3082\u3001\u3044\u304f\u3064\u304b\u3044\u305f\u3060\u3044\u3066\u3044\u307e\u3059\u3002\u79d1\u7814\u8cbb\u3063\u3066\u3044\u3046\u306e\u3082\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3057\u3001\u5b66\u4f1a\u3084\u8272\u3093\u306a\u3068\u3053\u308d\u306b\u51fa\u308b\u65c5\u8cbb\u3082\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3057\u3001\u3042\u3068\u306f\u4eca\u5ea6\u3001\u6765\u5e74\u304b\u3089\u30a2\u30e1\u30ea\u30ab\u306b\u884c\u304f\u305f\u3081\u306e\u4e88\u7b97\u3082\u30012\u672c\u5f53\u305f\u3063\u3066\u30021\u672c\u306f\u8f9e\u9000\u3057\u3066\u3057\u307e\u3046\u3093\u3067\u3059\u3051\u3069\u3001\u3053\u3046\u3055\u305b\u3066\u3082\u3089\u3063\u305f\u306e\u3082\u3001\u304d\u3061\u3093\u3068\u7814\u7a76\u8005\u3068\u3057\u3066\u78e8\u3044\u3066\u3044\u305f\u3060\u3044\u305f\u304b\u3089\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\r\n

\u3000\u7814\u7a76\u8005\u3068\u3057\u3066\u3084\u3063\u3066\u3044\u304f\u306b\u306f\u8272\u3005\u306a\u80fd\u529b\u304c\u3044\u308b\u3093\u3067\u3059\u3051\u308c\u3069\u3082\u3001\u5b9f\u9a13\u3092\u304d\u3061\u3093\u3068\u51fa\u6765\u308b\u3068\u3044\u3046\u306e\u306f\u3082\u3061\u308d\u3093\u5fc5\u8981\u3067\u3059\u3057\u3001\u81ea\u5206\u3067\u8003\u3048\u3066\u30c6\u30fc\u30de\u3092\u4f5c\u308b\u3068\u3044\u3046\u306e\u3082\u5fc5\u8981\u3060\u3068\u601d\u3044\u307e\u3059\u3057\u3001\u3042\u3068\u3001\u3053\u306e\u7814\u7a76\u5ba4\u3067\u3051\u3063\u3053\u3046\u5927\u4e8b\u306b\u3055\u308c\u3066\u3044\u308b\u306e\u306f\u3001\u300c\u66f8\u304f\u80fd\u529b\u300d\u3068\u3044\u3046\u306e\u304c\u3042\u3063\u3066\u3001\u81ea\u5206\u3067\u6587\u7ae0\u3092\u66f8\u3044\u3066\u3001\u305d\u308c\u3067\u7814\u7a76\u4e88\u7b97\u3092\u8cb0\u3063\u3066\u304d\u305f\u308a\u3068\u304b\u3001\u8ad6\u6587\u3092\u901a\u3057\u305f\u308a\u3068\u304b\u3001\u305d\u3046\u3044\u3046\u80fd\u529b\u304c\u5fc5\u8981\u306b\u306a\u308a\u307e\u3059\u3002\u3046\u3061\u306e\u7814\u7a76\u5ba4\u3067\u306f\u305d\u3053\u3092\u3057\u3063\u304b\u308a\u935b\u3048\u3066\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\r\n

\u7814\u7a76\u8005\u3068\u3057\u3066\u306e\u3053\u308c\u304b\u3089<\/h2>\r\n

\u2015\u2015\u305d\u3046\u3044\u3046\u7814\u7a76\u5ba4\u306e\u826f\u3055\u3092\u3001\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u3067\u4f1d\u3048\u3089\u308c\u305f\u3089\u3068\u601d\u3044\u307e\u3059\u3002\u3053\u308c\u304b\u3089\u3001\u7814\u7a76\u3092\u3053\u3093\u306a\u98a8\u306b\u3084\u3063\u3066\u3044\u304d\u305f\u3044\u3001\u3068\u3044\u3046\u4e8b\u306f\u3042\u308a\u307e\u3059\u304b\uff1f<\/p>\r\n

\u3000\u5c06\u6765\u3001\u3053\u308c\u304b\u3089\u3067\u3059\u304b\uff1f\u3000\u3048\u3063\u3068\u3067\u3059\u306d\u3001\u5317\u5927\u306b\u3044\u308b\u9593\u306f\u3059\u3054\u304f\u9811\u5f35\u3063\u3066\u3084\u3063\u305f\u3093\u3067\u3059\u3051\u3069\u3001\u7814\u7a76\u7d50\u679c\u3092\u3001\u3044\u308f\u3086\u308b\u30c8\u30c3\u30d7\u30af\u30e9\u30b9\u306e\u96d1\u8a8c\u306b\u8f09\u305b\u308b\u3053\u3068\u306f\u51fa\u6765\u306a\u304b\u3063\u305f\u3093\u3067\u3059\u3002\u6700\u65b0\u306e\u7814\u7a76\u6210\u679c\u306f\u3001\u3055\u304d\u307b\u3069\u304a\u8a71\u3057\u305fATF5\uff08\u203b\u77f3\u539f\u3055\u3093\u306e\u7814\u7a76\u300c\u653e\u5c04\u7dda\u8010\u6027\u3092\u3082\u3064\u3001\u304c\u3093\u306e\u60aa\u6027\u5316\u306b\u3064\u3044\u3066\u300d\u306f2015\u5e743\u6708\u3054\u308d\u516c\u958b\u4e88\u5b9a\u3067\u3059\uff09\u3092\u300cOncotarget\uff08\u30aa\u30f3\u30b3\u30bf\u30fc\u30b2\u30c3\u30c8\uff09<\/a>\u300d\u3068\u3044\u3046\u6240\u306b\u63b2\u8f09\u3057\u3066\u3044\u305f\u3060\u3044\u305f\u3093\u3067\u3059\u3051\u3069\u3001\u300cNature\uff08\u30cd\u30a4\u30c1\u30e3\u30fc\uff09\u300d\u3068\u304b\u300cScience\uff08\u30b5\u30a4\u30a8\u30f3\u30b9\uff09\u300d\u3068\u3044\u3046\u3068\u3066\u3082\u6709\u540d\u306a\u96d1\u8a8c\u304c\u3042\u308a\u307e\u3057\u3066\u3001\u3044\u305a\u308c\u306f\u305d\u306e\u3088\u3046\u306a\u96d1\u8a8c\u306b\u51fa\u3059\u3053\u3068\u3092\u76ee\u6a19\u306b\u3084\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u306b\u5fc5\u8981\u306a\u306e\u306f\u3001\u304a\u305d\u3089\u304f\u3001\u3082\u3063\u3068\u79c1\u81ea\u8eab\u306e\u30a2\u30a4\u30c7\u30a2\u3092\u78e8\u304b\u306a\u3051\u308c\u3070\u3044\u3051\u306a\u3044\u306e\u3068\u3001\u3042\u3068\u306f\u7814\u7a76\u8005\u3068\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u5927\u4e8b\u3060\u3068\u601d\u3046\u3093\u3067\u3059\u3088\u306d\u3002\u304c\u3093\u3092\u7814\u7a76\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u79c1\u306f\u7d30\u80de\u3092\u4f7f\u3063\u3066\u3084\u3063\u3066\u3044\u308b\u3093\u3067\u3059\u3051\u308c\u3069\u3082\u3001\u533b\u5e2b\u306e\u65b9\u3005\u3068\u5354\u529b\u3057\u305f\u65b9\u304c\u826f\u304b\u3063\u305f\u308a\u3001\u3042\u3068\u306f\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u306e\u5c02\u9580\u5bb6\u306e\u65b9\u3005\u3067\u3059\u3068\u304b\u3001\u305d\u3046\u3044\u3046\u4eba\u305f\u3061\u3068\u4e00\u7dd2\u306b\u306a\u3063\u3066\u4f5c\u3063\u3066\u3044\u3051\u3070\u3001\u304a\u305d\u3089\u304f\u3001\u30cd\u30a4\u30c1\u30e3\u30fc\u306a\u3069\u3082\u76ee\u6307\u305b\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u601d\u3046\u306e\u3067\u3002<\/p>\r\n

\u2015\u2015\u7814\u7a76\u30c1\u30fc\u30e0\u3092\u4f5c\u308b\u3068\u3044\u3046\u4e8b\u3067\u3059\u304b\uff1f<\/p>\r\n

\u3000\u305d\u3046\u3067\u3059\u306d\u3001\u624b\u52a9\u3051\u3057\u3066\u304f\u308c\u308b\u5c02\u9580\u306e\u65b9\u3068\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u4f5c\u3063\u3066\u3001\u6700\u7d42\u7684\u306b\u306f\u305d\u3046\u3044\u3046\u30c1\u30fc\u30e0\u3092\u4f5c\u3063\u3066\u3001\u3059\u3054\u304f\u826f\u3044\u7814\u7a76\u3092\u3084\u3063\u3066\u3001\u305d\u308c\u3067\u4e16\u754c\u306e\u8ab0\u3082\u601d\u3044\u3064\u304b\u306a\u304b\u3063\u305f\u3088\u3046\u306a\u3001\u304c\u3093\u6cbb\u7642\u6cd5\u3092\u78ba\u7acb\u3057\u3066\u3001\u300c\u304c\u3093\u3092\u64b2\u6ec5\u3060\uff01\u300d\u3068\u3044\u3046\u4e8b\u3092\u3001\u58f0\u3092\u5927\u306b\u3057\u3066\u8a00\u3048\u308b\u3088\u3046\u306a\u6642\u4ee3\u3092\u4f5c\u308a\u305f\u3044\u3001\u3068\u3044\u3046\u5922\u306f\u3042\u308a\u307e\u3059\u2026\u2026\u3053\u308c\u3001\u9332\u97f3\u3055\u308c\u3066\u308b\u3093\u3067\u3059\u3088\u306d\uff1f\uff08\u7b11\uff09<\/p>\r\n

\u2015\u2015\u9332\u97f3\u3055\u308c\u3066\u3044\u307e\u3059\uff01\uff08\u7b11\uff09 \u3067\u306f\u3001\u6d77\u5916\u306b\u65c5\u7acb\u305f\u308c\u308b\u5148\u8f29\u304b\u3089\u306e\u7f6e\u304d\u571f\u7523\u3068\u3057\u3066\u3001\u5f8c\u8f29\u306b\u6b8b\u3057\u3066\u3082\u3089\u3044\u305f\u3044\u30b3\u30e1\u30f3\u30c8\u306a\u306e\u3067\u3059\u304c\u3001\u4eca\u306e\u7814\u7a76\u5ba4\u3067\u300c\u3082\u3063\u3068\u3053\u3046\u3060\u3063\u305f\u3089\u3044\u3044\u306a\u300d\u3068\u601d\u3046\u3053\u3068\u306f\u3042\u308a\u307e\u3059\u304b\uff1f<\/p>\r\n

\u3000\u3046\u30fc\u3093\u3001\u305d\u3046\u3067\u3059\u306d\u2026\u2026\u3046\u3061\u306e\u7814\u7a76\u5ba4\u306f\u57fa\u672c\u7684\u306b\u3001\u3072\u3068\u308a\u3067\u7814\u7a76\u3092\u3084\u308b\u3093\u3067\u3059\u3002\u5b66\u751f\u3055\u3093\u3072\u3068\u308a\u3072\u3068\u308a\u304c\u3001\u305d\u308c\u305e\u308c\u3072\u3068\u3064\u306e\u30c6\u30fc\u30de\u3092\u6301\u3063\u3066\u3084\u3063\u3066\u3044\u304f\u306e\u3067\u3001\u5927\u304d\u306a\u7814\u7a76\u306b\u306f\u4ed5\u4e0a\u304c\u308a\u306b\u304f\u3044\u3093\u3067\u3059\u3088\u3002\u305f\u3068\u3048\u3070\u4e00\u4eba\u306e\u5148\u751f\u304c\u5c45\u3066\u3001\u5b66\u751f\u3055\u3093\u3001\u52a9\u624b\u3001\u8077\u54e1\u3001\u307f\u305f\u3044\u306b\u56e3\u4f53\u3067\u7814\u7a76\u3059\u308b\u3068\u3001\u77ed\u6642\u9593\u3067\u305f\u304f\u3055\u3093\u306e\u4e8b\u304c\u540c\u6642\u306b\u51fa\u6765\u307e\u3059\u304b\u3089\u3001\u7814\u7a76\u306f\u9032\u3080\u3093\u3067\u3059\u3088\u306d\u3002\u3059\u3054\u304f\u5927\u91cf\u306e\u5b9f\u9a13\u304c\u51fa\u6765\u3066\u3001\u5de8\u5927\u306a\u7814\u7a76\u304c\u5b8c\u6210\u3057\u3084\u3059\u3044\u3093\u3067\u3059\u3051\u3069\u3001\u3046\u3061\u306f\u3001\u305d\u306e\u3084\u308a\u65b9\u304c\u51fa\u6765\u306a\u3044\u3093\u3067\u3059\u3002\u5b66\u751f\u3055\u3093\u540c\u58eb\u304c\u7d44\u3093\u3067\u3072\u3068\u3064\u306e\u7814\u7a76\u3092\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u3092\u3001\u5148\u751f\u306e\u65b9\u91dd\u3067\u3046\u3061\u3067\u306f\u3084\u308a\u307e\u305b\u3093\u306e\u3067\u3001\u3072\u3068\u308a\u3072\u3068\u308a\u304c\u500b\u5225\u306e\u30c6\u30fc\u30de\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u4ed6\u306e\u7814\u7a76\u5ba4\u304c\u5927\u52e2\u3067\u3084\u3063\u3066\u3044\u308b\u3088\u3046\u306a\u5b9f\u9a13\u3092\u30011\u4eba\u3067\u3084\u3089\u306a\u3051\u308c\u3070\u3044\u3051\u306a\u3044\u3088\u3046\u306a\u3053\u3068\u3082\u3001\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\r\n

\u3000\u306a\u306e\u3067\u3001\u305d\u308c\u3067\u3082\u4e0a\u306b\u884c\u304f\u306b\u306f\u3069\u3046\u3059\u308b\u304b\u3063\u3066\u3044\u3046\u3068\u3001\u304a\u305d\u3089\u304f\u300c\u3059\u3054\u3044\u7814\u7a76\u8a08\u753b\u3092\u7df4\u308b\u3053\u3068\u300d\u3068\u3001\u300c\u3059\u3054\u304f\u826f\u3044\u30a2\u30a4\u30c7\u30a2\u3092\u6301\u3064\u300d\u3053\u3068\u304c\u5fc5\u8981\u306a\u306e\u3067\u3001\u305d\u3053\u3092\u610f\u8b58\u3057\u305f\u7814\u7a76\u3068\u3044\u3046\u306e\u306f\u9593\u9055\u3044\u306a\u304f\u5fc5\u8981\u304b\u306a\u3068\u601d\u3044\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u300c\u3059\u3054\u3044\u52b9\u7387\u5316\u300d\u3060\u3063\u305f\u308a\u3001\u982d\u306e\u4f7f\u3044\u65b9\u304c\u91cd\u8981\u306b\u306a\u3063\u3066\u304f\u308b\u3068\u601d\u3046\u3093\u3067\u3059\u3088\u306d\u3002\u306a\u306e\u3067\u3001\u305d\u3046\u3044\u3046\u6240\u3092\u305c\u3072\u8003\u3048\u306a\u304c\u3089\u3001\u5f8c\u8f29\u305f\u3061\u306b\u306f\u7814\u7a76\u3092\u3084\u3063\u3066\u6b32\u3057\u3044\u306a\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\r\n

\u2015\u2015\u305d\u308c\u306f\u3001\u7686\u3067\u3072\u3068\u3064\u306e\u30c6\u30fc\u30de\u3092\u7814\u7a76\u3059\u308b\u3053\u3068\u3092\u53d6\u308a\u5165\u308c\u3066\u3044\u3063\u305f\u3089\u826f\u3044\u3001\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u306a\u3044\u3093\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\r\n

\"\"<\/p>\r\n

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