{"id":1842,"date":"2015-03-17T15:10:08","date_gmt":"2015-03-17T06:10:08","guid":{"rendered":"http:\/\/altair.sci.hokudai.ac.jp\/g3\/?page_id=1842"},"modified":"2015-04-16T14:19:00","modified_gmt":"2015-04-16T05:19:00","slug":"res_01","status":"publish","type":"page","link":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/research\/res_01\/","title":{"rendered":"\u7814\u7a76\u300c\u7d30\u80de\u306e\u96c6\u56e3\u904b\u52d5\u3068\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u3064\u3044\u3066\u300d"},"content":{"rendered":"<p class=\"leadTxt\">\u7d30\u80de\u306b\u3082\u30ea\u30fc\u30c0\u30fc\u304c\u3044\u308b\uff01\u3000\u305d\u306e\u6027\u8cea\u3092\u63a2\u308b<\/p>\r\n<p>\u3000\u7d30\u80de\u306e\u96c6\u56e3\u904b\u52d5\u304c\u3069\u3046\u3084\u3063\u3066\u8d77\u304d\u3066\u3044\u308b\u306e\u304b\u3001\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u8abf\u3079\u3066\u3044\u307e\u3059\u3002<br \/>\u3000\u30a4\u30f3\u30c8\u30ed\u30c0\u30af\u30b7\u30e7\u30f3\u3068\u3057\u3066\u3001\u7d30\u80de\u306f\u52d5\u304f\u3068\u3044\u3046\u304a\u8a71\u3092\u3057\u307e\u3059\u3002\u4eba\u9593\u306e\u4f53\u306f\u7d0460\u5146\u500b\u306e\u7d30\u80de\u304b\u3089\u4f5c\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7d30\u80de\u306f\u751f\u547d\u306e\u6700\u5c0f\u5358\u4f4d\u3068\u3057\u3066\u3001\u3072\u3068\u3064\u3072\u3068\u3064\u304c\u751f\u547d\u6d3b\u52d5\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u305d\u308c\u305e\u308c\u306e\u7d30\u80de\u304c\u81ea\u5f8b\u7684\u306b\u52d5\u304f\u3053\u3068\u306f\u308f\u305f\u3057\u305f\u3061\u306e\u751f\u547d\u7dad\u6301\u306b\u3068\u3063\u3066\u5fc5\u8981\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\r\n<p>\u3000<img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1971\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_01.jpg\" alt=\"res_1_01\" width=\"200\" height=\"200\" \/>\u305f\u3068\u3048\u3070\u3001\u3053\u308c\u306f\u3068\u3066\u3082\u6709\u540d\u306a\u52d5\u753b\u306e\u4e00\u90e8\u3067\u3001\u30d0\u30af\u30c6\u30ea\u30a2\u3092\u8ffd\u8de1\u3059\u308b\u597d\u4e2d\u7403\uff08\u3053\u3046\u3061\u3085\u3046\u304d\u3085\u3046\uff09\u304c\u5199\u3063\u3066\u3044\u307e\u3059\u3002\u5c0f\u3055\u306a\u9ed2\u3044\u70b9\u304c\u30d0\u30af\u30c6\u30ea\u30a2\u3067\u3001\u5e73\u305f\u304f\u5927\u304d\u3044\u306e\u304c\u597d\u4e2d\u7403\u3001\u6570\u304c\u591a\u304f\u4e38\u3044\u306e\u306f\u8d64\u8840\u7403\u3067\u3059\u3002\u597d\u4e2d\u7403\u3068\u306f\u30d0\u30af\u30c6\u30ea\u30a2\u3092\u98df\u3079\u308b\u767d\u8840\u7403\u306e\u4e00\u7a2e\u3067\u3001\u30d0\u30af\u30c6\u30ea\u30a2\u3092\u305a\u3063\u3068\u8ffd\u3044\u56de\u3057\u3001\u6700\u5f8c\u306f\u4f53\u5185\u306b\u53ce\u3081\u3066\u5206\u89e3\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u306a\u305c\u3053\u306e\u3088\u3046\u306a\u3053\u3068\u304c\u8d77\u304d\u308b\u304b\u3068\u8a00\u3044\u307e\u3059\u3068\u3001\u597d\u4e2d\u7403\u304c\u30d0\u30af\u30c6\u30ea\u30a2\u306e\u51fa\u3059\u5316\u5b66\u7269\u8cea\u306b\u53cd\u5fdc\u3057\u3001\u305d\u306e\u65b9\u5411\u306b\u52d5\u304f\u305f\u3081\u3060\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u6709\u5bb3\u306a\u30d0\u30af\u30c6\u30ea\u30a2\u3082\u591a\u3044\u3067\u3059\u304b\u3089\u3001\u3053\u306e\u3088\u3046\u306b\u3001\u7d30\u80de\u304c\u904b\u52d5\u3057\u306a\u3051\u308c\u3070\u751f\u547d\u306f\u7dad\u6301\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\r\n<p>\u3000\u3053\u306e\u5199\u771f\u306b\u306f\u3072\u3068\u3064\u306e\u597d\u4e2d\u7403\u304c\u5199\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u7d30\u80de\u306f\u3044\u3064\u3082\u4e00\u3064\u305a\u3064\u30d0\u30e9\u30d0\u30e9\u306a\u306e\u304b\u3068\u3044\u3046\u3068\u3001\u305d\u308c\u306f\u9055\u3044\u307e\u3059\u3002\u591a\u304f\u306e\u7d30\u80de\u304c\u3001\u5225\u306e\u7d30\u80de\u3068\u4e00\u7dd2\u306b\u3044\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u30ab\u30a8\u30eb\u306e\u521d\u671f\u767a\u751f\u3067\u306f\u3001\u306f\u3058\u3081\u4e00\u3064\u306e\u53d7\u7cbe\u5375\u304b\u3089\u59cb\u307e\u308a\u3001\u5375\u5272\u3092\u7e70\u308a\u8fd4\u3059\u3053\u3068\u3067\u5272\u7403\u306e\u6570\u304c\u5897\u3048\u3066\u3001\u3084\u304c\u3066\u6570\u3048\u304d\u308c\u306a\u3044\u307b\u3069\u591a\u304f\u306e\u7d30\u80de\u304b\u3089\u6210\u308b\u80da\u3068\u306a\u308a\u307e\u3059\u3002\u30d2\u30c8\u3082\u540c\u3058\u3067\u3001\u7d30\u80de\u306f\u5e38\u306b\u5225\u306e\u7d30\u80de\u306b\u56f2\u307e\u308c\u3066\u3044\u308b\u3088\u3046\u306a\u72b6\u614b\u3067\u3059\u3002\u8840\u6db2\u7d30\u80de\u306e\u3088\u3046\u306b\u8840\u6d41\u306e\u4e2d\u306b\u3044\u308b\u7d30\u80de\u306f\u5358\u4e00\u3067\u3044\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u591a\u304f\u306e\u7d30\u80de\u306f\u96a3\u306e\u7d30\u80de\u3068\u63a5\u3057\u3066\u3044\u3066\u3001\u305f\u3068\u3048\u3070\u6e80\u54e1\u96fb\u8eca\u306e\u4e2d\u306b\u3044\u308b\u3088\u3046\u306a\u30a4\u30e1\u30fc\u30b8\u3067\u3059\u3002<\/p>\r\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1972\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_02.jpg\" alt=\"res_1_02\" width=\"200\" height=\"62\" \/>\u3000\u4e0a\u76ae\u7d30\u80de\uff08\u3058\u3087\u3046\u3072\u3055\u3044\u307c\u3046\uff09\u3068\u3044\u3046\u76ae\u819a\u306e\u4e00\u756a\u4e0a\u306e\u7d30\u80de\u306f\u3001\u6a21\u5f0f\u56f3\u306e\u3088\u3046\u306b\u7d30\u80de\u304c\u4e00\u500b\u4e00\u500b\u4e26\u3093\u3067\u96a3\u540c\u58eb\u3068\u304f\u3063\u3064\u304d\u3042\u3044\u300130\u4eba31\u811a\u306e\u3088\u3046\u306b\u304c\u3063\u3061\u308a\u80a9\u3092\u7d44\u3093\u3067\u3044\u307e\u3059\u3002<br \/>\u3053\u306e\u3088\u3046\u306b\u96a3\u306e\u7d30\u80de\u3068\u304c\u3063\u3061\u308a\u304f\u3063\u3064\u3044\u3066\u3044\u308b\u3053\u3068\u306f\u3068\u3066\u3082\u91cd\u8981\u3067\u3059\u3002\u76ae\u819a\u306f\u5e38\u306b\u5916\u304b\u3089\u306e\u523a\u6fc0\u306b\u3055\u3089\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e0a\u76ae\u7d30\u80de\u540c\u58eb\u304c\u9699\u9593\u306a\u304f\u304f\u3063\u3064\u3044\u3066\u3044\u306a\u3044\u3068\u75c5\u539f\u4f53\u304c\u4f53\u306b\u5165\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u88cf\u3092\u8fd4\u305b\u3070\u3001\u4e0a\u76ae\u7d30\u80de\u306f\u96a3\u540c\u58eb\u3067\u304f\u3063\u3064\u3044\u3066\u3001\u30d0\u30ea\u30a2\u306e\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u3059\u3002<\/p>\r\n<p>\u3000\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u30ab\u30a8\u30eb\u306e\u4f8b\u3067\u3082\u308f\u304b\u308b\u3088\u3046\u306b\u3001\u53d7\u7cbe\u5375\u304b\u3089\u6210\u4f53\u306b\u306a\u308b\u9014\u4e2d\u3067\u306f\u3001\u305d\u306e\u3088\u3046\u306a\u5bc6\u306b\u304f\u3063\u3064\u3044\u3066\u3044\u308b\u7d30\u80de\u3082\u52d5\u304b\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u300130\u4eba31\u811a\u3092\u601d\u3044\u51fa\u3057\u3066\u3044\u305f\u3060\u304f\u3068\u30a4\u30e1\u30fc\u30b8\u3057\u3084\u3059\u3044\u3088\u3046\u306b\u3001\u96a3\u306e\u4eba\u3068\u304c\u3063\u3061\u308a\u80a9\u3092\u7d44\u3093\u3067\u307f\u3093\u306a\u3067\u52d5\u304f\u306e\u306f\u96e3\u3057\u3044\u73fe\u8c61\u3067\u3059\u3002\u305d\u3053\u3067\u3001\u3053\u306e\u3088\u3046\u306b\u3057\u3063\u304b\u308a\u304f\u3063\u3064\u304d\u3042\u3063\u305f\u72b6\u614b\u3067\u3069\u3046\u3084\u3063\u3066\u7d30\u80de\u304c\u52d5\u304f\u306e\u304b\u3001\u7d30\u80de\u96c6\u56e3\u306b\u4f55\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u304b\u3092\u63a2\u308b\u3068\u3044\u3046\u4e8b\u304c\u3001\u3053\u306e\u7814\u7a76\u306e\u5185\u5bb9\u3067\u3059\u3002<\/p>\r\n<h2>\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306e\u767b\u5834<\/h2>\r\n<div class=\"clr alignright f12 alright\"><iframe loading=\"lazy\" frameborder=\"0\" height=\"190\" src=\"https:\/\/www.youtube.com\/embed\/S0_h7qy9yco?rel=0&amp;autohide=1\" width=\"250\"><\/iframe> <br \/>N. Yamaguchi, et al., Sci Rep, 2015<\/div>\r\n<p>\u3000\u3053\u3053\u304b\u3089\u306f\u3001\u5177\u4f53\u7684\u306a\u7814\u7a76\u306e\u304a\u8a71\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u30a4\u30cc\u814e\u5c3f\u7d30\u7ba1\u4e0a\u76ae\u7d30\u80de\uff08MDCK\uff09\u3068\u3044\u3046\u7d30\u80de\u3092\u4f7f\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u4e0a\u76ae\u7531\u6765\u306e\u7d30\u80de\u3067\u3059\u306e\u3067\u3001\u7d30\u80de\u540c\u58eb\u304c\u9699\u9593\u306a\u304f\u304c\u3063\u3061\u308a\u304f\u3063\u3064\u3044\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3092\u57f9\u990a\u76bf\u306b\u6492\u304f\u3068\u3001\u7d30\u80de\u540c\u58eb\u306f\u304f\u3063\u3064\u3044\u3066\u7d30\u80de\u30b7\u30fc\u30c8\u306b\u306a\u308a\u307e\u3059\u3002\u3057\u3070\u3089\u304f\u3059\u308b\u3068\u3001\u3068\u3064\u305c\u3093\u5148\u982d\u3092\u6b69\u304f\u5927\u304d\u306a\u7d30\u80de\u304c\u3042\u3089\u308f\u308c\u3001\u5468\u308a\u306e\u7d30\u80de\u3068\u307f\u3093\u306a\u3067\u540c\u3058\u65b9\u5411\u306b\u904b\u52d5\u3092\u59cb\u3081\u307e\u3059\u3002\u3053\u306e\u5927\u304d\u304f\u3066\u7279\u5fb4\u7684\u306a\u7d30\u80de\u306e\u3053\u3068\u3092\u3001\u79c1\u305f\u3061\u306f\u300c\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u300d\u3068\u547c\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\r\n<p><a href=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_04.jpg\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1973\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_03.jpg\" alt=\"res_1_03\" width=\"200\" height=\"200\" \/><\/a>\u3053\u306e\u3088\u3046\u306b\u3001\u7d30\u80de\u540c\u58eb\u304c\u304f\u3063\u3064\u3044\u305f\u72b6\u614b\u3067\u3001\u307f\u306a\u540c\u3058\u65b9\u5411\u306b\u52d5\u304f\u73fe\u8c61\u306e\u3053\u3068\u3092\u3001\u7d30\u80de\u306e\u96c6\u56e3\u904b\u52d5\u3068\u8a00\u3044\u307e\u3059\u3002\u3053\u306e\u73fe\u8c61\u306f\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u3066\u3001\u4e16\u754c\u4e2d\u3067\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\r\n<p>\u3000\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306e\u5f8c\u308d\u306b\u304f\u3063\u3064\u3044\u3066\u304f\u308b\u7d30\u80de\u306f\u3001\u30ea\u30fc\u30c0\u30fc\u3092\u30d5\u30a9\u30ed\u30fc\u3059\u308b\uff08\u3064\u3044\u3066\u3086\u304f\uff09\u4e8b\u304b\u3089\u300c\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u300d\u3068\u547c\u3070\u308c\u307e\u3059\u3002\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u305f\u3061\u306f\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u7387\u3044\u3089\u308c\u308b\u5f62\u3067\u3001\u96c6\u56e3\u3067\u540c\u3058\u65b9\u5411\u306b\u52d5\u304d\u307e\u3059\u3002\u3053\u306e\u753b\u50cf\u3067\u306f\u3001\u7d30\u80de\u304c\u6b21\u306b\u9032\u3080\u65b9\u5411\u3092\u8272\u3067\u8868\u73fe\u3057\u3066\u3044\u307e\u3059\u3002\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u3044\u308b\u3068\u304d\u306f\u3001\u307b\u3068\u3093\u3069\u306e\u7d30\u80de\u304c\u7dd1\u3068\u9ec4\u8272\u306e\u8272\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u3053\u306e\u753b\u50cf\u306e\u306a\u304b\u3067\u30010\u5ea6\u304b\u308945\u5ea6\u304f\u3089\u3044\u306e\u65b9\u5411\u306b\u5411\u3051\u3066\u904b\u52d5\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u3092\u4eba\u5de5\u7684\u306b\u6d88\u3057\u3066\u3057\u307e\u3063\u305f\u3089\u3069\u3046\u306a\u308b\u306e\u304b\u3001\u3068\u3044\u3046\u5b9f\u9a13\u3092\u3084\u308a\u307e\u3057\u305f\u3002<\/p>\r\n<h2>\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u6d88\u3048\u3066\u3057\u307e\u3046\u3068\u3001\u3069\u3046\u306a\u308b\uff1f<\/h2>\r\n<div class=\"clr alignright f12 alright\"><iframe loading=\"lazy\" frameborder=\"0\" height=\"190\" src=\"https:\/\/www.youtube.com\/embed\/DKQe8ZDmA8A?rel=0&amp;autohide=1\" width=\"250\"><\/iframe> <br \/>N. Yamaguchi, et al., Sci Rep, 2015<\/div>\r\n<p>\u3000\u9855\u5fae\u93e1\u3067\u898b\u306a\u304c\u3089\u3001\u30ac\u30e9\u30b9\u306e\u91dd\u3067\u30d7\u30c1\u30c3\u3068\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u3092\u7a81\u304d\u523a\u3057\u307e\u3059\u3002\u3059\u308b\u3068\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u3060\u3051\u304c\u6b7b\u306b\u3001\u305d\u3053\u3067\u96c6\u56e3\u904b\u52d5\u304c\u30b9\u30c8\u30c3\u30d7\u3057\u307e\u3057\u305f\u3002\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u793a\u3057\u3066\u3044\u305f\u9032\u884c\u65b9\u5411\u304c\u306a\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u3001\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u306f\u305d\u308c\u4ee5\u4e0a\u524d\u306b\u9032\u3081\u306a\u304f\u306a\u3063\u3066\u3001\u6e0b\u6ede\u306e\u3088\u3046\u306a\u5f62\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u5f8c\u308d\u306e\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u305f\u3061\u306f\u3001\u3050\u308b\u3050\u308b\u3068\u3001\u30d0\u30e9\u30d0\u30e9\u306e\u65b9\u5411\u306b\u52d5\u304f\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\r\n<p class=\"clr\"><a href=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_06.jpg\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1976\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_05.jpg\" alt=\"res_1_05\" width=\"200\" height=\"200\" \/><\/a>\u3000\u3053\u3053\u3067\u306f\u904b\u52d5\u306e\u901f\u5ea6\u3082\u8a08\u7b97\u3057\u307e\u3057\u3066\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u3044\u306a\u304f\u306a\u308b\u3068\u3001\u904b\u52d5\u306e\u901f\u5ea6\u3082\u9045\u304f\u306a\u308b\u4e8b\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\r\n<p><!--<img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1970\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_11.jpg\" alt=\"res_1_11\" width=\"200\" height=\"200\" \/>-->\u3000\u3053\u308c\u3089\u306e\u4e8b\u304b\u3089\u3001\u7d30\u80de\u306e\u96c6\u56e3\u904b\u52d5\u3067\u306e\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306e\u91cd\u8981\u6027\u304c\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306f\u3001\u304a\u305d\u3089\u304f\u904b\u52d5\u306e\u65b9\u5411\u3092\u6c7a\u3081\u3066\u3044\u3066\u3001\u306a\u304a\u304b\u3064\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u305f\u3061\u3092\u5f15\u3063\u5f35\u3063\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3001\u3068\u3044\u3046\u4e8b\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u3092\u9664\u3044\u3066\u3057\u307e\u3063\u305f\u5f8c\u306b\u3001\u5225\u306e\u7d30\u80de\u304c\u30ea\u30fc\u30c0\u30fc\u306b\u306a\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3069\u3046\u3057\u3066\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u73fe\u308c\u308b\u306e\u304b\u306f\u307e\u3060\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u3001\u5927\u304d\u306a\u30af\u30a8\u30b9\u30c1\u30e7\u30f3\u3068\u3057\u3066\u3001\u73fe\u5728\u9032\u884c\u5f62\u306e\u7814\u7a76\u30c6\u30fc\u30de\u3067\u3059\u3002<\/p>\r\n<h2>\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306e\u7279\u5fb4\u3068\u306f<\/h2>\r\n<p>\u3000\u6b21\u306b\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u304a\u8a71\u3057\u307e\u3059\u3002\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306f\u3001\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u306e\u524d\u3067\u6d3b\u767a\u306b\u904b\u52d5\u3057\u307e\u3059\u3002\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u306f\u3001\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u306b\u6bd4\u3079\u3066\u6d3b\u6027\u5316\u3057\u3066\u3044\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u307e\u3057\u305f\u3002\u4f8b\u3092\u3042\u3052\u307e\u3059\u3068\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306f\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u3088\u308a\u3082\u5927\u304d\u306a\u30a8\u30f3\u30b8\u30f3\u3092\u7a4d\u3093\u3067\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u305d\u306e\u30a8\u30f3\u30b8\u30f3\u306f\u4f55\u304b\uff1f\u3000\u3068\u3044\u3046\u306e\u304c\u6b21\u306e\u554f\u3044\u3067\u3057\u305f\u3002<\/p>\r\n<p>\u3000\u7d30\u80de\u304c\u52d5\u304f\u6642\u306b\u5fc5\u8981\u306aRac1\uff08\u30e9\u30c3\u30af\u30ef\u30f3\uff09\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u30b9\u30a4\u30c3\u30c1\u306e\u3088\u3046\u306a\u3082\u306e\u3068\u8003\u3048\u3066\u4e0b\u3055\u3044\u3002\u308f\u304b\u308a\u3084\u3059\u304f\u8a00\u3044\u307e\u3059\u3068\u3001Rac1\u304c\u30aa\u30f3\u306b\u306a\u308b\u3068\u7d30\u80de\u904b\u52d5\u304c\u6d3b\u6027\u5316\u3055\u308c\u3066\u3088\u304f\u52d5\u304f\u3088\u3046\u306b\u306a\u308a\u3001\u9006\u306b\u30aa\u30d5\u306b\u306a\u308b\u3068\u3001\u7d30\u80de\u306f\u52d5\u304b\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\r\n<p><a href=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_08.jpg\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1975\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_07.jpg\" alt=\"res_1_07\" width=\"200\" height=\"147\" \/><\/a>\u3000\u305d\u3053\u3067\u3001\u907a\u4f1d\u5b50\u7d44\u63db\u3048\u6280\u8853\u3068\u7dd1\u8272\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6280\u8853\u3092\u4f7f\u3063\u3066\u3001\u30b9\u30a4\u30c3\u30c1\u304c\u30aa\u30f3\u306e\u6642\u306eRac1\u3060\u3051\u3092\u5149\u3089\u305b\u308b\u3088\u3046\u306b\u3057\u307e\u3057\u305f\u3002<br \/>\u4e0b\u6751\u8129\u5148\u751f\u304cGFP\uff08\u7dd1\u8272\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u3092\u30aa\u30ef\u30f3\u30af\u30e9\u30b2\u304b\u3089\u5206\u96e2\u3057\u307e\u3057\u3066\u30ce\u30fc\u30d9\u30eb\u8cde\u3092\u53d7\u8cde\u3055\u308c\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u6280\u8853\u3067\u3059\u3002\u3053\u308c\u3067\u3001\u7d30\u80de\u306e\u4e2d\u3067\u30b9\u30a4\u30c3\u30c1\u304c\u30aa\u30f3\u306b\u306a\u3063\u305fRac1\u306e\u5834\u6240\u304c\u308f\u304b\u308a\u307e\u3059\u3002<\/p>\r\n<p class=\"clr\">\u3000\u89b3\u5bdf\u3057\u307e\u3059\u3068\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306e\u5148\u982d\u90e8\u5206\u306b\u3001\u30b9\u30a4\u30c3\u30c1\u30aa\u30f3\u306eRac1\u304c\u96c6\u307e\u3063\u3066\u3044\u308b\u3068\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u5f8c\u308d\u306e\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u306f\u3001\u305d\u3046\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u3002\u8272\u5473\u304c\u86cd\u5149\u306e\u5f37\u3055\u3092\u8868\u3057\u3066\u3044\u3066\u3001\u30ab\u30e9\u30fc\u30d0\u30fc\u306e\u4e0a\u306b\u884c\u304f\u307b\u3069\uff08\u767d\u306b\u8fd1\u3065\u304f\u307b\u3069\uff09\u5f37\u304f\u306a\u308a\u307e\u3059\u3002\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u3067\u306f\u3001\u5148\u982d\u304c\u767d\u3068\u30aa\u30ec\u30f3\u30b8\u3067\u5f8c\u65b9\u304c\u6c34\u8272\u304b\u3089\u9752\u3068\u3044\u3046\u3088\u3046\u306b\u3001\u904b\u52d5\u306e\u65b9\u5411\u306b\u5bfe\u3057\u3066\u3001\u30b9\u30a4\u30c3\u30c1\u30aa\u30f3\u306eRac1\u304c\u30b0\u30e9\u30c7\u30fc\u30b7\u30e7\u30f3\u306b\u306a\u3063\u3066\u3044\u308b\u306e\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\r\n<div class=\"clr alignright f12 alright\"><iframe loading=\"lazy\" frameborder=\"0\" height=\"190\" src=\"https:\/\/www.youtube.com\/embed\/lmFPEAgTeG8?rel=0&amp;autohide=1\" width=\"250\"><\/iframe> <br \/>N. Yamaguchi, et al., Sci Rep, 2015<\/div>\r\n<p>\u3000\u3067\u306f\u9006\u306b\u3001\u904b\u52d5\u306e\u9014\u4e2d\u3067\u3001Rac1\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u30aa\u30d5\u306b\u3057\u305f\u3089\u3069\u3046\u306a\u308b\u306e\u304b\u3068\u8003\u3048\u3001\u305d\u306e\u3088\u3046\u306a\u5b9f\u9a13\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u904b\u52d5\u4e2d\u306bRac1\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u30aa\u30d5\u306b\u3059\u308b\u85ac\u3092\u5165\u308c\u308b\u3068\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306f\u5c0f\u3055\u304f\u306a\u3063\u3066\u52d5\u304b\u306a\u304f\u306a\u308a\u3001\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u306f\u3050\u308b\u3050\u308b\u56de\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u85ac\u3092\u6d17\u3044\u6d41\u3057\u3066\u3042\u3052\u308b\u3068\u3001\u3075\u305f\u305f\u3073\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306f\u5927\u304d\u304f\u306a\u308a\u3001\u96c6\u56e3\u904b\u52d5\u304c\u56de\u5fa9\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u3067\u3001Rac1\u306e\u30b9\u30a4\u30c3\u30c1\u304c\u30aa\u30d5\u306e\u6642\u306b\u306f\u96c6\u56e3\u904b\u52d5\u304c\u3067\u304d\u306a\u3044\u3068\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\r\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1968\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_09.jpg\" alt=\"res_1_09\" width=\"200\" height=\"200\" \/>\u3000\u6b21\u306b\u3001\u7d30\u80de\u306e\u4e2d\u306b\u3042\u308b\u3001Rac1\u306e\u30aa\u30f3\u3068\u30aa\u30d5\u306e\u30b9\u30a4\u30c3\u30c1\u306e\u5272\u5408\u3092\u5909\u3048\u308b\u3088\u3046\u306a\u5b9f\u9a13\u3092\u3057\u307e\u3057\u305f\u3002\u56f3\u306e\u4e2d\u306e\u8d64\u3044\u7d30\u80de\u306f\u30b9\u30a4\u30c3\u30c1\u304c\u6b63\u5e38\u306aRac1\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u7dd1\u8272\u306e\u7d30\u80de\u306f\u3001\u5916\u304b\u3089\u30aa\u30d5\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u305f\u304f\u3055\u3093\u5165\u308c\u3066\u3001\u307b\u3068\u3093\u3069\u30aa\u30d5\u306e\u30b9\u30a4\u30c3\u30c1\u3057\u304b\u6301\u3063\u3066\u3044\u306a\u3044\u72b6\u614b\u306b\u3057\u305f\u7d30\u80de\u3067\u3059\u3002\u305d\u3053\u3067\u4e09\u901a\u308a\u306e\u57f9\u990a\u3092\u3057\u3066\u307f\u307e\u3057\u305f\u3002<\/p>\r\n<p>\u3000\u4e00\u3064\u3081\u306f\u3001\u6b63\u5e38\u306a\u30b9\u30a4\u30c3\u30c1\u3092\u6301\u3063\u3066\u3044\u308b\u8d64\u306e\u7d30\u80de\u3060\u3051\u3002\u4e8c\u3064\u3081\u306f\u3001\u30aa\u30d5\u306e\u30b9\u30a4\u30c3\u30c1\u3070\u304b\u308a\u6301\u3063\u3066\u3044\u308b\u7dd1\u306e\u7d30\u80de\u3060\u3051\u3002\u4e09\u3064\u3081\u306f\u3001\u8d64\u3068\u7dd1\u306e\u7d30\u80de\u30921\u5bfe99\u3067\u6df7\u305c\u307e\u3057\u305f\u3002<\/p>\r\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1969\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2015\/03\/res_1_10.jpg\" alt=\"res_1_10\" width=\"200\" height=\"200\" \/>\u3000\u3059\u308b\u3068\u3001\u8d64\u3044\u7d30\u80de\u3064\u307e\u308a\u6b63\u3057\u3044\u30b9\u30a4\u30c3\u30c1\u3092\u6301\u3063\u3066\u3044\u308b\u7d30\u80de\u3060\u3051\u306e\u6642\u306f\u3001\u3060\u3044\u305f\u3044\u3072\u3068\u3064\u306e\u74b0\u5883\u304b\u308913\u3050\u3089\u3044\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u51fa\u3066\u304d\u307e\u3057\u305f\u3002\u4e00\u65b9\u3001\u30aa\u30d5\u306e\u30b9\u30a4\u30c3\u30c1\u3070\u304b\u308a\u6301\u3063\u3066\u3044\u308b\u7dd1\u306e\u7d30\u80de\u3067\u306f\u3001\u307b\u3068\u3093\u3069\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u51fa\u3066\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u8d64\u3068\u7dd1\u304c1\u5bfe99\u3068\u3044\u3046\u5272\u5408\u3067\u3001\u8d64\u306e\u7d30\u80de\u3092\u6975\u7aef\u306b\u5c11\u306a\u304f\u6df7\u305c\u305f\u3082\u306e\u3067\u306f\u3001\u8d64\u306e\u7d30\u80de\u304c\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u3068\u306a\u308a\u96c6\u56e3\u904b\u52d5\u3057\u307e\u3057\u305f\u3002<br \/>\u3053\u308c\u306b\u3088\u308a\u3001Rac1\u304c\u6b63\u5e38\u306b\u50cd\u304b\u306a\u3044\u9650\u308a\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u306f\u306a\u308c\u306a\u3044\u3068\u3044\u3046\u4e8b\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\r\n<p>\u3000\u307e\u305f\u3001Rac1\u306b\u52a0\u3048\u3066\u3001\u4e8c\u3064\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u6ce8\u76ee\u3057\u3066\u540c\u3058\u3088\u3046\u306a\u5b9f\u9a13\u3092\u3057\u307e\u3057\u305f\u3002\u7d30\u80de\u5185\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u4e92\u3044\u306b\u95a2\u4fc2\u3057\u5408\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u306f\u3001\u30b9\u30a4\u30c3\u30c1\u3092\u9806\u756a\u306b\u5165\u308c\u3066\u3044\u304f\u3088\u3046\u306a\u30a4\u30e1\u30fc\u30b8\u3067\u3059\u3002\u6700\u521d\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u5165\u308c\u308b\u3068\u3072\u3068\u3064\u96fb\u706f\u304c\u70b9\u3044\u3066\u3001\u3059\u308b\u3068\u305d\u306e\u96a3\u306e\u96fb\u706f\u304c\u3064\u3044\u3066\u3001\u3068\u3053\u306e\u3088\u3046\u306a\u4ed5\u7d44\u307f\u3092\u30b7\u30b0\u30ca\u30eb\u30ab\u30b9\u30b1\u30fc\u30c9\u3068\u3044\u3044\u307e\u3059\u3002\u4eca\u56de\u306f\u308f\u304b\u308a\u3084\u3059\u304fRac1\u306b\u7d5e\u3063\u3066\u304a\u8a71\u3055\u305b\u3066\u3082\u3089\u3044\u307e\u3057\u305f\u3002<\/p>\r\n<p>\u3000\u307e\u3068\u3081\u307e\u3059\u3068\u3001MDCK\u7d30\u80de\u3092\u98fc\u3063\u3066\u3044\u307e\u3059\u3068\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u304c\u51fa\u3066\u304d\u3066\u3001\u30d5\u30a9\u30ed\u30ef\u30fc\u7d30\u80de\u3092\u9023\u308c\u308b\u3088\u3046\u306b\u96c6\u56e3\u904b\u52d5\u3092\u8d77\u3053\u3057\u307e\u3059\u3002\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306f\u96c6\u56e3\u904b\u52d5\u306b\u3068\u3063\u3066\u91cd\u8981\u306a\u5b58\u5728\u3067\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u3067\u3042\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u3042\u308b\u3068\u3044\u3046\u4e8b\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\r\n<p>\u3000\u3057\u304b\u3057\u3001\u3053\u3053\u307e\u3067\u306e\u5185\u5bb9\u3067\u3059\u3068\u3001\u300cRac1\u304c\u6d3b\u6027\u5316\u3057\u3066\u3044\u308b\u304b\u3089\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u306a\u308b\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u306a\u308b\u3068Rac1\u304c\u6d3b\u6027\u5316\u3059\u308b\u306e\u304b\uff1f\u300d\u308f\u304b\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u305f\u3081\u3001\u6b21\u306e\u8ab2\u984c\u3068\u3057\u3066\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u306a\u308b\u305f\u3081\u306e\u30c8\u30ea\u30ac\u30fc\u3068\u306a\u308b\u6027\u8cea\u3092\u63a2\u3057\u3066\u3044\u307e\u3059\u3002\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3057\u305f\u3002<br \/><br \/><a class=\"icoBlank\" href=\"http:\/\/www.nature.com\/srep\/2015\/150107\/srep07656\/full\/srep07656.html\" target=\"_blank\">\u3053\u306e\u7814\u7a76\u306e\u8ad6\u6587\u3092\u8aad\u3080\uff08\u82f1\u6587\uff09Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin \u03b21 and PI3K<\/a><\/p>\r\n<p class=\"clr\"><a class=\"icoLink\" title=\"\u7814\u7a76\u300c\u96c6\u56e3\u3067\u52d5\u304f\u7d30\u80de\uff081\uff09\u4e0a\u76ae\u7d30\u80de\u306e\u6298\u308a\u8fd4\u3057\u904b\u52d5\u300d\" href=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/research\/res_02\/\">\u7814\u7a76\u300c\u96c6\u56e3\u3067\u52d5\u304f\u7d30\u80de\uff081\uff09\u4e0a\u76ae\u7d30\u80de\u306e\u6298\u308a\u8fd4\u3057\u904b\u52d5\u300d\u3092\u8aad\u3080<\/a><\/p>\r\n<p style=\"text-align: right;\"><a class=\"icoLink\" title=\"\u7814\u7a76\u5185\u5bb9\" href=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/research\/\">\u7814\u7a76\u5185\u5bb9\u30ab\u30c6\u30b4\u30ea\u30fc\u30c8\u30c3\u30d7\u306b\u623b\u308b<\/a><\/p>\r\n","protected":false},"excerpt":{"rendered":"\u7d30\u80de\u306b\u3082\u30ea\u30fc\u30c0\u30fc\u304c\u3044\u308b\u306e\u3092\u77e5\u3063\u3066\u3044\u307e\u3059\u304b\uff1f\r\n\u304c\u3063\u3061\u308a\u80a9\u3092\u7d44\u3093\u3060\u7d30\u80de\u305f\u3061\u306f\u3001\u30ea\u30fc\u30c0\u30fc\u7d30\u80de\u306b\u5c0e\u304b\u308c\u3066\u52d5\u304d\u307e\u3059\u3002\u30ea\u30fc\u30c0\u30fc\u306e\u6027\u8cea\u3068\u306f\u4f55\u306a\u306e\u3067\u3057\u3087\u3046\u304b\u3002 ","protected":false},"author":1,"featured_media":2038,"parent":9,"menu_order":220,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-1842","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/1842","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/comments?post=1842"}],"version-history":[{"count":33,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/1842\/revisions"}],"predecessor-version":[{"id":2485,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/1842\/revisions\/2485"}],"up":[{"embeddable":true,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/9"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/media\/2038"}],"wp:attachment":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/media?parent=1842"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}