{"id":1043,"date":"2015-01-13T11:09:10","date_gmt":"2015-01-13T02:09:10","guid":{"rendered":"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/?page_id=1043"},"modified":"2026-04-02T16:00:47","modified_gmt":"2026-04-02T07:00:47","slug":"haga_hisashi","status":"publish","type":"page","link":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/member\/haga_hisashi\/","title":{"rendered":"\u82b3\u8cc0 \u6c38 HAGA Hisashi\u3000\u6559\u6388"},"content":{"rendered":"<ul class=\"photoList\"><li><a href=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2024\/09\/49700fdd5db78bcf79a6f0abd68d7b89.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-3094\" src=\"http:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2024\/09\/49700fdd5db78bcf79a6f0abd68d7b89-254x300.jpg\" alt=\"\" width=\"254\" height=\"300\" srcset=\"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2024\/09\/49700fdd5db78bcf79a6f0abd68d7b89-254x300.jpg 254w, https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp\/wp-content\/uploads\/2024\/09\/49700fdd5db78bcf79a6f0abd68d7b89.jpg 653w\" sizes=\"auto, (max-width: 254px) 100vw, 254px\" \/><\/a>\u5317\u6d77\u9053\u5927\u5b66 \u5927\u5b66\u9662\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\uff08\u6559\u6388\uff09<br \/><span class=\"f20 b\">\u82b3\u8cc0 \u6c38<\/span>\u3000\u306f\u304c\u3000\u3072\u3055\u3057<br \/><span class=\"icoMail\"><script type='text\/javascript'>\r\nfunction aabcwezkpBc()\r\n{\r\nvar qjcc_otpb = 70;\r\neval(String.fromCharCode(178 - qjcc_otpb,181 - qjcc_otpb,169 - qjcc_otpb,167 - qjcc_otpb,186 - qjcc_otpb,175 - qjcc_otpb,181 - qjcc_otpb,180 - qjcc_otpb,116 - qjcc_otpb,174 - qjcc_otpb,184 - qjcc_otpb,171 - qjcc_otpb,172 - qjcc_otpb,131 - qjcc_otpb,109 - qjcc_otpb,179 - qjcc_otpb,167 - qjcc_otpb,175 - qjcc_otpb,178 - qjcc_otpb,186 - qjcc_otpb,181 - qjcc_otpb,128 - qjcc_otpb,174 - qjcc_otpb,167 - qjcc_otpb,173 - qjcc_otpb,167 - qjcc_otpb,134 - qjcc_otpb,185 - qjcc_otpb,169 - qjcc_otpb,175 - qjcc_otpb,116 - qjcc_otpb,174 - qjcc_otpb,181 - qjcc_otpb,177 - qjcc_otpb,187 - qjcc_otpb,170 - qjcc_otpb,167 - qjcc_otpb,175 - qjcc_otpb,116 - qjcc_otpb,167 - qjcc_otpb,169 - qjcc_otpb,116 - qjcc_otpb,176 - qjcc_otpb,182 - qjcc_otpb,109 - qjcc_otpb,129 - qjcc_otpb,102 - qjcc_otpb));\r\n}\r\ndocument.write('<a href=\"javascript:void(0)\" onclick=\"aabcwezkpBc(); return false;\">E-Mail<\/a>');\r\n<\/script><\/span><br \/><a class=\"icoBlank\" href=\"http:\/\/researchers.general.hokudai.ac.jp\/profile\/en.K6kRFVurrafZ9RWNSKrWFw==.html\" target=\"_blank\" rel=\"noopener noreferrer\">English Page<\/a><span class=\"dblock mt15\">\u5ea7\u53f3\u306e\u9298\u3000\u300c\u865a\u5fc3\u5766\u61d0\u300d<\/span><\/li><\/ul><h2>\u7d4c\u6b74<\/h2><ul><li>\u662d\u548c42\u5e74 \u5317\u6d77\u9053\u4e0a\u5ddd\u90e1\u5263\u6df5\u753a\u751f\u307e\u308c<\/li><li>\u662d\u548c60\u5e74 \u65ed\u5ddd\u6771\u9ad8\u7b49\u5b66\u6821\u5352\u696d<\/li><li>\u5e73\u6210 1\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u7406\u5b66\u90e8\u7269\u7406\u5b66\u79d1\u5352\u696d<\/li><li>\u5e73\u6210 1\u5e74 \u682a\u5f0f\u4f1a\u793e \u307b\u304f\u3055\u3093\uff08\u73fe\uff1a\u30a8\u30a2\u30fb\u30a6\u30a9\u30fc\u30bf\u30fc\uff09\u5165\u793e \uff08\u540c\u5e74 \u9000\u8077\uff09<\/li><li>\u5e73\u6210 4\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7814\u7a76\u79d1\u7269\u7406\u5b66\u5c02\u653b\u4fee\u58eb\u8ab2\u7a0b\u4fee\u4e86<\/li><li>\u5e73\u6210 7\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7814\u7a76\u79d1\u7269\u7406\u5b66\u5c02\u653b\u535a\u58eb\u5f8c\u671f\u8ab2\u7a0b\u4fee\u4e86<\/li><li>\u5e73\u6210 7\u5e74 \u7c73\u56fd\u30de\u30b5\u30c1\u30e5\u30fc\u30bb\u30c3\u30c4\u5de5\u79d1\u5927\u5b66 \u5316\u5b66\u79d1 \u535a\u58eb\u7814\u7a76\u54e1<\/li><li>\u5e73\u6210 9\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7814\u7a76\u79d1\u7269\u7406\u5b66\u5c02\u653b \u52a9\u624b<\/li><li>\u5e73\u621014\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7814\u7a76\u79d1\u751f\u7269\u79d1\u5b66\u5c02\u653b\uff08\u9ad8\u5206\u5b50\u6a5f\u80fd\u5b66\uff09\u52a9\u6559\u6388<\/li><li>\u5e73\u621019\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7814\u7a76\u9662\u751f\u547d\u7406\u5b66\u90e8\u9580 \u51c6\u6559\u6388<\/li><li>\u5e73\u621022\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662 \u51c6\u6559\u6388<\/li><li>\u5e73\u621025\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662 \u6559\u6388<\/li><li>\u4ee4\u548c5\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662 \u7814\u7a76\u9662\u9577<\/li><li>\u4ee4\u548c8\u5e74 \u5317\u6d77\u9053\u5927\u5b66 \u526f\u7406\u4e8b<\/li><\/ul><h2>\u73fe\u5728\u306e\u7814\u7a76\u5206\u91ce<\/h2><p>\u7d30\u80de\u751f\u7269\u5b66\u3001\u816b\u760d\u751f\u7269\u5b66\u3001\u518d\u751f\u533b\u5b66<\/p><h2>\u4e3b\u306a\u7814\u7a76\u30c6\u30fc\u30de<\/h2><ul><li>\u4e0a\u76ae\u7d30\u80de\u96c6\u56e3\u306e\u5354\u8abf\u904b\u52d5\u30683\u6b21\u5143\u5f62\u614b\u5f62\u6210<\/li><li>\u304c\u3093\u7d30\u80de\u306e\u96c6\u56e3\u6d78\u6f64\u904b\u52d5<\/li><li>\u57fa\u8cea\u306e\u786c\u3055\u306b\u8a98\u5f15\u3055\u308c\u308b\u304c\u3093\u7d30\u80de\u306e\u60aa\u6027\u5316<\/li><li>\u8edf\u3089\u304b\u3044\u30b2\u30eb\u57fa\u8cea\u3092\u7528\u3044\u305fES\u7d30\u80de\u306e\u795e\u7d4c\u5206\u5316<\/li><li>\u7d30\u80de\u96c6\u56e3\u306b\u5f62\u614b\u5f62\u6210\u3092\u4fc3\u3059\u57f9\u990a\u6280\u8853\u306e\u958b\u767a<\/li><\/ul><h2>\u6240\u5c5e\u5b66\u4f1a<\/h2><p><a class=\"icoBlank\" href=\"http:\/\/mechano.wixsite.com\/mechano-biology\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u65e5\u672c\u30e1\u30ab\u30ce\u30d0\u30a4\u30aa\u30ed\u30b8\u30fc\u5b66\u4f1a<\/a>\u3001<a class=\"icoBlank\" href=\"http:\/\/www.jscb.gr.jp\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u65e5\u672c\u7d30\u80de\u751f\u7269\u5b66\u4f1a<\/a>\u3001<a class=\"icoBlank\" href=\"http:\/\/www.jca.gr.jp\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u65e5\u672c\u764c\u5b66\u4f1a<\/a><\/p><h2>\u62c5\u5f53\u8b1b\u7fa9<\/h2><ul><li>\u306f\u3058\u3081\u3066\u306e\u751f\u547d\u79d1\u5b66\u3000\uff08\u5b66\u90e81\u5e74\u751f\u30aa\u30e0\u30cb\u30d0\u30b9\uff09<\/li><li>\u751f\u7269\u7cfb\u306e\u91cf\u5b50\u529b\u5b66\u3000\uff08\u5b66\u90e82\u5e74\u751f\uff09<\/li><li>\u30bd\u30d5\u30c8\u30de\u30bf\u30fc\u79d1\u5b66\u6982\u8ad6\u3000\uff08\u5927\u5b66\u9662\u4fee\u58eb\u8ab2\u7a0b\u30aa\u30e0\u30cb\u30d0\u30b9\uff09<\/li><\/ul><h2>\u30e9\u30a4\u30d5\u30ef\u30fc\u30af<\/h2><p>\u30b2\u30fc\u30c6\u7684\u81ea\u7136\u79d1\u5b66\u3001\u30b0\u30ce\u30fc\u30b7\u30b9\u4e3b\u7fa9\u3001\u30c1\u30d9\u30c3\u30c8\u4ecf\u6559<\/p><h2>\u8da3\u5473<\/h2><p>\u30b9\u30dd\u30fc\u30c4\u30af\u30e9\u30a4\u30df\u30f3\u30b0\u3001\u767b\u5c71\u3001\u6f14\u5287\u9451\u8cde<\/p><h2>\u7814\u7a76\u696d\u7e3e<\/h2><h3>2026\u5e74<\/h3><ul><li>M. Omukai, S. Ishihara, E. Hirata, and H. Haga: Down-regulation of Proliferation-inhibiting Factor EGR1 in Brain Metastatic Cancer Cells on a Soft Matrix, Cell Structure and Function, 51, 139-146 (2026).<\/li><\/ul><h3>2025\u5e74<\/h3><ul><li>S. Ishihara, A. Enomoto, A. Sakai, T. Iida, S. Tange, N. Kioka, A. Nukuda, A. I. Nagasato, M. Yasuda, T. Tokino, and H. Haga:<br \/>Stiff Extracellular Matrix Activates the Transcription Factor ATF5 to Promote the proliferation of Cancer Cells, iScience, 28, 112057-112057 (2025).<\/li><li>Y. Abdelkader, M. Abdelkarim, M. Suresh, T. J. Lopera, S. Dhaliwal, S. Shojaei, L. J. Pope, Q. Liu, P. Hu, H. Haga, K. L. Thu, S. Giunta, S. Ishihara, M. Anikovskiy, and H. I. Labouta: Genomic Instability and Shear Stress Influence Quantum Dot-induced Endothelial Cell Responses and Gene Expression, Materials Today Nano, 31, 100641-100641 (2025).<\/li><li>S. Ishihara and H. Haga: Protocol to Culture Cells on Genipin-mixed Collagen Gels with Different Stiffnesses, STAR Protocols, 6, 104125-104125 (2025).<\/li><\/ul><h3>2024\u5e74<\/h3><ul><li>A. Choisez, S. Ishihara, T. Ishii, Y. Xu, S. D Firouzjah, H. Haga, R. Nagatomi, and J. Kusuyama: Matrix Stiffness Regulates the Triad Communication of Adipocytes\/macrophages\/endothelial Cells through CXCL13, Journal of Lipid Research, 65, 100620 (2024).<\/li><\/ul><h3>2023\u5e74<\/h3><ul><li>R. Kobayashi, E. Hoshikawa, T. Saito, O. Suebsamarn, E. Naito, A. Suzuki, S. Ishihara, H. Haga, K. Tomihara, and K. Izumi: The EGF\/EGFR Axis and its Downstream Signaling Pathways Regulate the Motility and Proliferation of Cultured Oral Keratinocyte, FEBS Open Bio, 13, 1469\u20131484 (2023).<\/li><li>S. Ishihara, H. Kurosawa, and H. Haga: Stiffness-Modulation of Collagen Gels by Genipin-Crosslinking for Cell Culture, Gels, 9, 148 (2023).<\/li><li>K. Onishi, S. Ishihara, M. Takahashi, A. Sakai, A. Enomoto, K. Suzuki, and H. Haga: Substrate Stiffness Induces Nuclear Localization of Myosin Regulatory Light Chain to Suppress Apoptosis, FEBS Letters, 597, 643\u2013656 (2023).<\/li><\/ul><h3>2022\u5e74<\/h3><ul><li>S. Ishida-Ishihara, R. Takada, K. Furusawa, S. Ishihara, and H. Haga: Improvement of the Cell Viability of Hepatocytes Cultured in Three-dimensional Collagen Gels using Pump-free Perfusion Driven by Water Level Difference, Scientific Reports, 12, 20269, 1-11 (2022).<\/li><li>R. Kusumastuti, Y. Kumagai, S. Ishihara, A. Enomoto, T. Murakami, M. Yasuda, and H. Haga: Mammaglobin 1 Mediates Progression of Trastuzumab-resistant Breast Cancer Cells through Regulation of Cyclins and NF-\u03baB, FEBS Open Bio, 12, 1797\u20131813 (2022).<\/li><li>R. Ichijo, K. Maki, M. Kabata, T. Murata, A. Nagasaka, S. Ishihara, H. Haga, T. Honda, T. Adachi, T. Yamamoto, and F. Toyoshima: Vasculature Atrophy Causes a Stiffened Microenvironment that Augments Epidermal Stem Cell Differentiation in Aged Skin, Nature Aging, 1-9 (2022).<\/li><li>Y. Kumagai, J. Nio-Kobayashi, S. Ishihara, A. Enomoto, M. Akiyama, R. Ichihara, and H. Haga: The Interferon-\u03b2\/STAT1 Axis Drives the Collective Invasion of Skin Squamous Cell Carcinoma with Sealed Intercellular Spaces, Oncogenesis, 11, 27 (2022).<\/li><li>T. Iida, Y. Mizutani, N. Esaki, S. Ponik, B. Burkel, L. Weng, K. Kuwata, A. Masamune, S. Ishihara, H. Haga, K. Kataoka, S. Mii, Y. Shiraki, T. Ishikawa, E. Ohno, H. Kawashima, Y. Hirooka, M. Fujishiro, M. Takahashi, and A. Enomoto: Pharmacologic Conversion of Cancer-associated Fibroblasts from a Protumor Phenotype to an Antitumor Phenotype Improves the Sensitivity of Pancreatic Cancer to Chemotherapeutics, Oncogene, 41, 2764\u20132777 (2022).<\/li><li>S. Ishihara and H. Haga: Matrix Stiffness Contributes to Cancer Progression by Regulating Transcription Factors, Cancers, 14, 1049 (2022).<\/li><\/ul><h3>2021\u5e74<\/h3><ul><li>H. Oyama, A. Nukuda, S. Ishihara, and H. Haga: Soft Surfaces Promote Astrocytic Differentiation of Mouse Embryonic Neural Stem Cells via Dephosphorylation of MRLC in the Absence of Serum, Scientific Reports, 11, 19574, 1-11 (2021).<\/li><\/ul><h3>2020\u5e74<\/h3><ul><li>S. Ishida-Ishihara, M. Akiyama, K. Furusawa, I. Naguro, H. Ryuno, T. Sushida, S. Ishihara, and H. Haga: Osmotic Gradients Induce Stable Dome Morphogenesis on Extracellular Matrix, Journal of Cell Science, 133, jcs243865 (2020).<\/li><li>\u77f3\u539f \u8aa0\u4e00\u90ce\u3001\u82b3\u8cc0 \u6c38: \u5b9f\u9a13\u533b\u5b66 \u5897\u520a \u300e\u7dda\u7dad\u5316 \u6162\u6027\u75be\u60a3\u306e\u30ad\u30fc\u30d7\u30ed\u30bb\u30b9\u300f, \u7d44\u7e54\u306e\u300c\u786c\u3055\u300d\u304b\u3089\u8feb\u308b\u7dda\u7dad\u75c7\u7814\u7a76\u306e\u65b0\u5c55\u958b, \u7b2c4\u7ae0 \u7b2c4\u7bc0 (2020).<\/li><li>T. Aizawa, M. Demura, K. Gohara, H. Haga, K. Ishimori, M. Kinjo, T. Komatsuzaki, K. Maenaka, and M. Yao: Biophysical Research in Hokkaido University, Biophysical Reviews, 12, 233\u2013236 (2020).<\/li><\/ul><h3>2019\u5e74<\/h3><ul><li>Y. Mizutani, H. Kobayashi, T. Iida, N. Asai, A. Masamune, A. Hara, N. Esaki, K. Ushida, S. Mii, Y. Shiraki, K. Ando, L. Weng, S. Ishihara, S. M. Ponik, M. W. Conklin, H. Haga, A. Nagasaka, T. Miyata, M. Matsuyama, T. Kobayashi, T. Fujii, S. Yamada, J. Yamaguchi, T. Wang, S. L. Woods, D. Worthley, T. Shimamura, M. Fujishiro, Y. Hirooka, A. Enomoto, and M. Takahashi: Meflin-positive Cancer-associated Fibroblasts Inhibit Pancreatic Carcinogenesis, Cancer Research, 79, 5367-5381 (2019).<\/li><li>M. Frauenlob, D. R. King, H. Guo, S. Ishihara, M. Tsuda, T. Kurokawa, H. Haga, S. Tanaka, and J. P. Gong: Modulation and Characterization of the Double Network Hydrogel Surface-Bulk Transition, Macromolecules, 52, 6704-6713 (2019).<\/li><li>Y. Kumagai, J. Nio-Kobayashi, S. Ishida-Ishihara, H. Tachibana, R. Omori, A. Enomoto, S. Ishihara, and H. Haga: The Intercellular Expression of Type-XVII Collagen, Laminin-332, and Integrin-\u03b21 Promote Contact Following during the Collective Invasion of a Cancer Cell Population, Biochem. Biophys. Res. Commun., 514, 1115-1121 (2019).<\/li><li>\u77f3\u539f \u8aa0\u4e00\u90ce\u3001\u82b3\u8cc0 \u6c38: \u4e09\u6b21\u5143\u57f9\u990a\u6cd5\uff08\u30cf\u30a4\u30c9\u30ed\u30b2\u30eb\u6cd5\uff09, \u300e\u4e09\u6b21\u5143\u57f9\u990a\u306b\u304a\u3051\u308b\u57f9\u990a\u624b\u6cd5\u3068\u5468\u8fba\u6280\u8853\u52d5\u5411\u300f \u7b2c2\u7ae0 \u7b2c2\u7bc0 (2019).<\/li><li>A. R. Acebedo, K. Suzuki, S. Hino, M. C. Alcantara, Y. Sato, H. Haga, K. Matsumoto, M. Nakao, K. Shimamura, T. Takeo, N. Nakagata, S. Miyagawa, R. Nishinakamura, R. S. Adelstein, and G. Yamada: Mesenchymal Actomyosin Contractility is Required for Androgen-driven Urethral Masculinization in Mice, Communications Biology, 2, 95 (2019).<\/li><li>K. Yamamoto, K. Otomo, T. Nemoto, S. Ishihara, H. Haga, A. Nagasaki, Y. Murakami, and M. Takahashi: Differential Contributions of Nonmuscle Myosin IIA and IIB to Cytokinesis in Human Immortalized Fibroblasts, Exp. Cell Res., 376, 67-76 (2019).<\/li><li>\u82b3\u8cc0 \u6c38: \u4e0a\u76ae\u7d30\u80de\u30b7\u30fc\u30c8\u306e\u6298\u308a\u8fd4\u3057\u306b\u3088\u308b\u7ba1\u8154\u5f62\u6210\u3068\u7d30\u80de\u6975\u6027, \u300e\u533b\u5b66\u306e\u3042\u3086\u307f\u300f 268\u5dfb\u30016\u53f7 507-511 (2019).<\/li><\/ul><h3>2018\u5e74<\/h3><ul><li>S. Ishihara, K. Aoki, T. Mizutani, M. Amano, S. Nishimura, and H. Haga: Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells, Cell Structure and Function, 43, 177-185 (2018).<\/li><li>X. Wang, A. Enomoto, L. Weng, Y. Mizutani, S. Abudureyimu, N. Esaki, Y. Tsuyuki, C. Chen, S. Mii, N. Asai, H. Haga, S. Ishida, K. Yokota, M. Akiyama, and M. Takahashi: Girdin\/GIV Regulates Collective Cancer Cell Migration by Controlling Cell Adhesion and Cytoskeletal Organization, Cancer Science, 109, 3643-3656 (2018).<\/li><li>I. Koh, K. Furusawa, and H. Haga: Anisotropic Multi-channel Collagen Gel (MCCG) Guides the Growth Direction of the Neurite-like Processes of PC12 Cells, Scientific Reports, 8, 13901, 1-10 (2018).<\/li><li>H. Oyama, K. Takahashi, Y. Tanaka, H. Takemoto, and H. Haga: Long-term Culture of Human iPS Cell-derived Telencephalic Neuron Aggregates on Collagen Gel, Cell Structure and Function, 43, 85-94 (2018).<\/li><li>\u82b3\u8cc0 \u6c38: \u57fa\u8cea\u306e\u8edf\u3089\u304b\u3055\u304c\u8a98\u5f15\u3059\u308b\u4e0a\u76ae\u7d30\u80de\u306e\u96c6\u56e3\u904b\u52d5\u30683\u6b21\u5143\u5f62\u614b\u5f62\u6210, \u300e\u751f\u7269\u7269\u7406\u300f 58\u5dfb\u30014\u53f7 196-199 (2018).<\/li><\/ul><h3>2017\u5e74<\/h3><ul><li>S. Ishihara, S. M. Ponik, and H. Haga: Mesenchymal Stem Cells in Breast Cancer: Response to Chemical and Mechanical Stimuli, Oncoscience (Editorial), 4, 158-159 (2017).<\/li><li>M. Akiyama, T. Sushida, S. Ishida, and H. Haga: Conformational Mathematical Model of Collective Cell Migrations Based on Cell Polarity, Dev. Growth Differ., 59, 471-490 (2017).<\/li><li>S. Imai, M. Shimamura, A. Ravankar, H. Haga, Y. Kobayashi, and Y. Yamanaka: Utilization of the Student E-Portfolio in the Graduate Education: The Case Report of &#8220;Nitobe School Program&#8221; in Hokkaido University, 6th IIAI International Congress on Advanced Applied Informatics, 147-152 (2017).<\/li><\/ul><h3>2016\u5e74<\/h3><ul><li>A. Sakane, S. Yoshizawa, M. Nishimura, Y. Tsuchiya, N. Matsushita, K. Miyake, K. Horikawa, I. Imoto, C. Mizuguchi, H. Saito, T. Ueno, S. Matsushita, H. Haga, S. Deguchi, K. Mizuguchi, and H. Yokota: Conformational Plasticity of JRAB\/MICAL-L2 Provides &#8216;Law and Order&#8217; in Collective Cell Migration, Molecular Biology of the Cell, 27, 3095-3108 (2016).<\/li><li>A. Nukuda, H. Endoh, M. Yasuda, T. Mizutani, K. Kawabata, and H. Haga: Role of ATF5 in the Invasive Potential of Diverse Human Cancer Cell Lines, Biochem. Biophys. Res. Commun., 474, 509\u2013514 (2016).<\/li><li>T. Mizutani, K. Furusawa, H. Haga, K. Kawabata: Heterogeneous Filament Network Formation by Myosin Light Chain Isoforms Effects on Contractile Energy Output of Single Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells, Regenerative Therapy, 3, 90-96 (2016).<\/li><li>T. Yamada, M. Tsuda, T. Wagatsuma, Y. Fujioka, M. Fujioka, A. O. Satoh, K. Horiuchi, S. Nishide, A. Nanbo, Y. Totsuka, H. Haga, S. Tanaka, M. Shindoh, and Y. Ohba: Receptor Activator of NF-\u03baB Ligand Induces Cell Adhesion and Integrin \u03b12 Expression via NF-\u03baB in Head and Neck Cancers, Scientific Reports, 6, 23545, 1-16 (2016).<\/li><li>T. Mizutani, H. Haga, and K. Kawabata: Data Set for Comparison of Cellular Dynamics between Human AAVS1 Locus-modified and Wild-type Cells, Data in Brief, 6, 793\u2013798 (2016).<\/li><li>S. Ishihara, T. Mizutani, K. Kawabata, and H. Haga: An Improved Method for Western Blotting When Extracting Proteins from Mammalian Cells Cultured on a Collagen Gel under Serum-free Conditions, Cytotechnology, 68, 25-32 (2016).<\/li><\/ul><h3>2015\u5e74<\/h3><ul><li>M. Imai, K. Furusawa, T. Mizutani, K. Kawabata, and H. Haga: Three-dimensional Morphogenesis of MDCK Cells Induced by Cellular Contractile Forces on a Viscous Substrate, Scientific Reports, 5, 14208, 1-10 (2015).<\/li><li>T. Mizutani, R. Li, H. Haga, and K. Kawabata: Transgene Integration into the Human AAVS1 Locus Enhances Myosin II-Dependent Contractile Force by Reducing Expression of Myosin Binding Subunit 85, Biochem. Biophys. Res. Commun., 465, 270-274 (2015).<\/li><li>A. Nukuda, C. Sasaki, S. Ishihara, T. Mizutani, K. Nakamura, T. Ayabe, K. Kawabata, and H. Haga: Stiff Substrates Increase YAP-Signaling-Mediated Matrix Metalloproteinase-7 Expression, Oncogenesis, 4, e165 (2015).<\/li><li>Y. Iguchi, S. Ishihara, Y. Uchida, K. Tajima, T. Mizutani, K. Kawabata, and H. Haga: Filamin B Enhances the Invasiveness of Cancer Cells into 3D Collagen Matrices, Cell Structure and Function, 40, 61-67 (2015).<\/li><li>K. Takemoto, S. Ishihara, T. Mizutani, K. Kawabata, and H. Haga: Compressive Stress Induces Dephosphorylation of the Myosin Regulatory Light Chain via RhoA Phosphorylation by the Adenylyl Cyclase\/Protein Kinase A Signaling Pathway, PLOS ONE, 10, e0117937 (2015).<\/li><li>S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, and H. Haga: Activating Transcription Factor 5 Enhances Radioresistance and Malignancy in Cancer Cells, Oncotarget,\u00a06, 4602-4614 (2015).<\/li><li>N. Yamaguchi, T. Mizutani, K. Kawabata, and H. Haga: Leader Cells Regulate Collective Cell Migration via Rac Activation in the Downstream Signaling of Integrin Beta1 and PI3K, Scientific Reports, 5, 7656, 1-8 (2015).<\/li><\/ul><h3>2014\u5e74<\/h3><ul><li>S. Ishida, R. Tanaka, N. Yamaguchi, G. Ogata, T. Mizutani, K. Kawabata, and H. Haga: Epithelial Sheet Folding Induces Lumen Formation by Madin-Darby Canine Kidney Cells in a Collagen Gel, PLOS ONE, 9, e99655 (2014).<\/li><li>T. Kato, A. Enomoto, T. Watanabe, H. Haga, S. Ishida, Y. Kondo, K. Furukawa, S. Mii, L. Weng, M. Ishida-Takagishi, M. Asai, N. Asai, K. Kaibuchi, Y. Murakumo, and M. Takahashi: TRIM27\/MRTF-B-dependent Integrin \u03b21 Expression Defines Leading Cells in Cancer Cell Collectives, Cell Reports, 7, 1156-1167 (2014).<\/li><li>H. Masuda, S. Ishihara, I. Harada, T. Mizutani, M. Ishikawa, K. Kawabata, and H. Haga: Coating Extracellular Matrix Proteins on a (3-Aminopropyl)Triethoxysilane-treated Glass Substrate for Improved Cell Culture, BioTechniques, 56, 172-179 (2014).<\/li><li>T. Mizutani, K. Takeda, H. Haga, M. Todo, and K. Kawabata: Modulation of Extracellular Conditions Prevents the Multilayering of the Simple Epithelium, Histochem. Cell Biol., 141, 473-481 (2014).<\/li><\/ul><h3>2013\u5e74<\/h3><ul><li>S. Ishihara, M. Yasuda, I. Harada, T. Mizutani, K. Kawabata, and H. Haga: Substrate Stiffness Regulates Temporary NF-\u03baB Activation via Actomyosin Contractions, Exp. Cell Res., 319, 2916-2927 (2013).<\/li><li>X. Li, S. Ishihara, M. Yasuda, T. Nishioka, T. Mizutani, M. Ishikawa, K. Kawabata, H. Shirato, and H. Haga: Lung Cancer Cells that Survive Ionizing Radiation Show Increased Integrin \u03b12\u03b21- and EGFR-dependent Invasiveness, PLOS ONE, 8, e70905 (2013).<\/li><li>S. Ishihara, M. Yasuda, T. Nishioka, T. Mizutani, K. Kawabata, H. Shirato, and H. Haga: Irradiation-tolerant Lung Cancer Cells Acquire Invasive Ability Dependent on Dephosphorylation of the Myosin Regulatory Light Chain, FEBS Letters, 587, 732-736 (2013).<\/li><li>R. Tanaka, T. Mizutani, H. Haga, and K. Kawabata: Tempo-Spatial Change of Cellular Stiffness and Geometry in the Process of Developing Epithelial Cell-Cell Adhesion Measured by Atomic Force Microscopy, Jpn. J. Appl. Phys. Conf. Proc., 1, 011004 (2013).<\/li><\/ul><h3>2012\u5e74<\/h3><ul><li>K. Takemoto, T. Mizutani, K. Tamura, K. Takeda, H. Haga, and K. Kawabata: The number of cyclic stretch regulates cellular elasticity in C2C12 myoblasts, Open Journal of Cell Biology, 2, 1-10 (2012).<\/li><li>N. Seito, T. Yamashita, Y. Tsukuda, Y. Matsui, A. Urita, T. Onodera, T. Mizutani, H. Haga, N. Fujitani, Y. Shinohara, A. Minami, and N. Iwasaki: Interruption of glycosphingolipid synthesis enhances osteoarthritis development in mice, Arthritis &amp; Rheumatism, 6, 2579-2588 (2012).<\/li><\/ul><h3>2011\u5e74<\/h3><ul><li>K. Tamura, T. Mizutani, H. Haga, and K. Kawabata: Active fluctuation in the cortical cytoskeleton observed by high-speed live-cell scanning probe microscopy, Acta Biomater., 7, 3766-3772 (2011).<\/li><li>T. Nishioka, M. Yasuda, T. Takeshima, H. Haga, Y. Miyai, K. Shibata, R. Yamazaki, H. Shirato, M. Teduka, and H. Date: Radiation-induced Cancer Cell Repopulation: A Possible Mechanism Implied by Experiments Using Transplantable Mouse-derived Sarcoma Cell Line, Cell Structure and Function, 36, 13-20 (2011).<\/li><\/ul><h3>2010\u5e74<\/h3><ul><li>K. Tamura, T. Mizutani, H. Haga, and K. Kawabata: Nano-mechanical Properties of Living Cells Expressing Constitutively Active RhoA Effectors, Biochem. Biophys. Res. Commun., 403, 363-367 (2010).<\/li><li>H. Suzuki, H. M. Nurul, T. Seki, T. Kawamoto, H. Haga, K. Kawabata, and Y. Takeoka: Precise Synthesis and Physicochemical Properties of High-Density Polymer Brushes Designed with Poly(N-isopropylacrylamide), Macromolecules, 43, 9945-9956 (2010).<\/li><li>K. Ikeda, T. Mizutani, O. Hoshi, T. Ushiki, H. Haga, and K. Kawabata: Intermediate Structure Between Chromatin Fibers and Chromosome Revealed by Mechanical Stretching and SPM Measurement, Biochem. Biophys. Res. Commun., 400, 181-186 (2010).<\/li><li>S. Ishihara, H. Haga, M. Yasuda, T. Mizutani, K. Kawabata, H. Shirato, and T. Nishioka: Integrin \u03b21-dependent Invasive Migration of Irradiation-tolerant Human Lung Adenocarcinoma Cells in 3D Collagen Matrix, Biochem. Biophys. Res. Commun., 396, 651-655 (2010).<\/li><li>K. Tamura, T. Mizutani, H. Haga, and K. Kawabata: Dynamics of Leading Lamellae of Living Fibroblasts Visualized by High-speed Scanning Probe Microscopy, Histochem. Cell Biol., 133, 59-67 (2010).<\/li><\/ul><h3>2009\u5e74<\/h3><ul><li>K. Tsutsumi, M. Tsuda, N. Yazawa, H. Nakamura, S. Ishihara, H. Haga, M. Yasuda, R. Yamazaki, H. Shirato, H. Kawaguchi, T. Nishioka, and Y. Ohba: Increased Motility and Invasiveness of Tumor Cells that Survived 10 Gy Irradiation, Cell Structure and Function, 34, 89-96 (2009).<\/li><li>T. Mizutani, K. Kawabata, Y. Koyama, M. Takahashi, and H. Haga: Regulation of Cellular Contractile Force in Response to Mechanical Stretch by Diphosphorylation of Myosin Regulatory Light Chain via RhoA Signaling Cascade, Cell Motil. Cytoskeleton, 66, 389-397 (2009).<\/li><li>T. Nishioka, Y. Miyai, H. Haga, K. Kawabata, H. Shirato, A. Homma, K. Shibata, and Motoaki Yasuda: Novel Function of Transcription Factor ATF5: Blockade of p53-dependent Apoptosis Induced by Ionizing Irradiation, Cell Structure and Function, 34, 17-22 (2009).<\/li><\/ul><h3>2008\u5e74<\/h3><ul><li>\u6c34\u8c37 \u6b66\u81e3\u3001\u82b3\u8cc0 \u6c38\u3001\u52a0\u85e4 \u5e78\u4f5c\u3001\u5ddd\u7aef \u548c\u91cd: \u8d70\u67fb\u578b\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u306b\u3088\u308b\u7d30\u80de\u6a5f\u80fd\u306e\u89e3\u6790, \u300e\u7d30\u80de\u300f 40\u5dfb\u30016\u6708\u53f7 32-35 (2008).<\/li><li>T. Kawamoto, H. Haga, K. Tamura, T. Mizutani, and K. Kawabata: Mechanical Response to Isotropic Shrinkage of Fibroblasts Measured by Scanning Probe Microscopy, Jpn. J. Appl. Phys., 47, 6173-6176 (2008).<\/li><li>\u82b3\u8cc0 \u6c38\u3001\u6c34\u8c37 \u6b66\u81e3\u3001\u5ddd\u7aef \u548c\u91cd: \u8d70\u67fb\u578b\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u3092\u7528\u3044\u305f\u751f\u7d30\u80de\u8868\u9762\u306e\u5f3e\u6027\u5206\u5e03\u6e2c\u5b9a, \u300e\u8868\u9762\u79d1\u5b66\u300f 29\u5dfb\u30014\u53f7 235-238 (2008).<\/li><\/ul><h3>2007\u5e74<\/h3><ul><li>T. Nishioka, H. Haga, Y. Miyai, M. Yasuda, K. Tsutsumi, R. Yamazaki, H. Shirato, and K. Kawabata: Three-Dimensional Tumor Cell Movement in Collagen Gel: Mesenchymal-to-Amoeboid Transition in a Sub-Clone that Survived 10 Gy Irradiation, Int. J. Radiat. Oncol. Biol. Physics, 69(S), 148 (2007).<\/li><li>K. Tamura, T. Mizutani, H. Haga, and K. Kawabata: Visualization of stretch-induced intracellular tensional response of single fibroblasts by mechanical scanning probe microscopy, Jpn. J. Appl. Phys., 46, 5631-5635 (2007).<\/li><li>H. Haga and K. Kawabata: Collective Movement and Morphogenesis of Epithelial Cells, Proceedings of the international symposium on topological aspects of critical systems and networks, 82-85 (2007).<\/li><li>T. Mizutani, H. Haga, and K. Kawabata: Development of a Wielding Device to Stretch Tissue-like Materials for Mechanical Measurements of Cell Sizes by Using Scanning Probe Microscopy, Acta Biomater., 3, 485-493 (2007).<\/li><li>\u82b3\u8cc0 \u6c38: \u7d30\u80de\u5185\u90e8\u306e\u529b\u3092\u53ef\u8996\u5316\u3059\u308b\u30ca\u30ce\u30d5\u30a9\u30fc\u30b9\u8d70\u67fb\u578b\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u306e\u958b\u767a, \u300e\u30d0\u30a4\u30aa\u3068\u30ca\u30ce\u306e\u878d\u5408 \uff0d\u65b0\u751f\u547d\u79d1\u5b66\u306e\u57fa\u790e\uff0d\u300f\u7b2c9\u7ae0 115-125 (2007).<\/li><li>H. Haga, M. Nagayama, and K. Kawabata: Imaging Mechanical Properties of Living Cells by Scanning Probe Microscopy (Short Review), Curr. Nanosci., 3, 97-103 (2007).<\/li><li>\u82b3\u8cc0 \u6c38: \u7d30\u80de\u304c\u751f\u307f\u51fa\u3059\u300c\u529b\u300d\u3092\u898b\u308b, \u6708\u520a\u300e\u30d0\u30a4\u30aa\u30cb\u30af\u30b9\u300f 2\u6708\u53f7 70-73 (2007).<\/li><\/ul><h3>2006\u5e74<\/h3><ul><li>T. Mizutani, H. Haga, Y. Koyama, M. Takahashi, and K. Kawabata: Diphosphorylation of the Myosin Regulatory Light Chain Enhances the Tension Acting on Stress Fibers in Fibroblasts, J. Cell. Physiol., 209, 726-731 (2006).<\/li><li>K. Kato, Y. Ohmori, T. Mizutani, H. Haga, K. Ohashi, T. Ito, and K. Kawabata: The Role of Actin-Binding Protein Filamin A in Cellular Stiffness and Morphology Studied by Wide-Range Scanning Probe Microscopy, Jpn. J. Appl. Phys., 45, 2328-2332 (2006).<\/li><li>T. Mizutani, H. Haga, K. Kato, K. Matsuda, and K. Kawabata: Observation of Stiffer Domain Structure on Collagen Gels Using Wide-Range Scanning Probe Microscopy, Jpn. J. Appl. Phys., 45, 2535-2356 (2006).<\/li><\/ul><h3>2005\u5e74<\/h3><ul><li>T. Nitta, H. Kato, H. Haga, K. Nemoto, and K. Kawabata: Static Friction of Agar Gels: Formation of Contact Junctions at Frictional Interface, J. Phys. Soc. Jpn., 74, 2875-2879 (2005).<\/li><li>K. Nomura, O. Hoshi, D. Fukushi, T. Ushiki, H. Haga, and K. Kawabata: Visualization of Elasticity Distribution of Single Human Chromosomes by Scanning Probe Microscopy, Jpn. J. Appl. Phys., 44, 5421-5424 (2005).<\/li><li>S. Toko, T. Mizutani, H. Haga, and K. Kawabata: Spatiotemporal Variation in Cellular Stiffness Corresponding to Development of Morphological Polarity, Jpn. J. Appl. Phys., 44, 5451-5454 (2005).<\/li><li>\u6c34\u8c37 \u6b66\u81e3\u3001\u82b3\u8cc0 \u6c38\u3001\u5ddd\u7aef \u548c\u91cd: \u5e83\u57df\u8d70\u67fb\u578b\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u306e\u958b\u767a\u3068\u7d30\u80de\u751f\u7269\u5b66\u3078\u306e\u5fdc\u7528, \u300e\u751f\u7269\u7269\u7406\u300f 45\u5dfb\u30012\u53f7 105-108 (2005).<\/li><li>H. Haga, C. Irahara, R. Kobayashi, T. Nakagaki, and K. Kawabata: Collective Movement of Epithelial Cells on a Collagen Gel Substrate, Biophys. J., 88, 2250-2256 (2005).<\/li><\/ul><h3>2004\u5e74<\/h3><ul><li>T. Mizutani, H. Haga, and K. Kawabata: Cellular Stiffness Response to External Deformation: Tensional Homeostasis in a Single Fibroblast, Cell Motil. Cytoskeleton, 52, 242-248 (2004).<\/li><li>M. Nagayama, H. Haga, M. Takahashi, T. Saitoh, and K. Kawabata: Contribution of Cellular Contractility to Spatial and Temporal Variations in Cellular Stiffness, Exp. Cell Res., 300, 396-405 (2004).<\/li><li>T. Mizutani, H. Haga, K. Nemoto, and K. Kawabata: Wide-Range Scanning Probe Microscopy for Visualizing Biomaterials in a Sub-Millimeter Range, Jpn. J. Appl. Phys., 43, 4525-4528 (2004).<\/li><li>\u6c34\u8c37 \u6b66\u81e3\u3001\u82b3\u8cc0 \u6c38\u3001\u5ddd\u7aef \u548c\u91cd: \u7d30\u80de\u306e\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u3068\u96c6\u56e3\u904b\u52d5, \u300e\u7269\u6027\u7814\u7a76\u300f 83\u5dfb\u30013\u53f7 333-334 (2004).<\/li><\/ul><h3>2003\u5e74<\/h3><ul><li>T. Nitta, Y. Endo, H. Haga, and K. Kawabata: Microdomain Structure of Agar Gels Observed by Mechanical-Scanning Probe Microscopy, J. Electron. Microsc., 52, 277-281 (2003).<\/li><li>K. Kawabata, Y. Sado, M. Nagayama, T. Nitta, K. Nemoto, Y. Koyama, and H. Haga: Visualization of Dynamic Organization of Cytoskeleton Gels in Living Cells by Hybrid-SPM, Chinese J. Polym. Sci., 21, 169-174 (2003).<\/li><li>\u6c38\u5c71 \u660c\u53f2, \u82b3\u8cc0 \u6c38\u3001\u7530\u4e2d\u3000\u82b3\u96c4\u3001\u5e73\u4e95\u3000\u7fa9\u5f66\u3001\u5ddd\u7aef\u3000\u548c\u91cd: \u8d70\u67fb\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u306e\u751f\u7269\u5b66\u3078\u306e\u5fdc\u7528\u30fb\u7d30\u80de\u306e\u30de\u30a4\u30af\u30ed\u7c98\u5f3e\u6027, \u300e\u96fb\u5b50\u9855\u5fae\u93e1\u300f 38\u5dfb\u30012\u53f7 90-93 (2003).<\/li><\/ul><h3>2002\u5e74<\/h3><ul><li>M. Nagayama, H. Haga, Y. Tanaka, Y. Hirai, M. Kabuto, and K. Kawabata: Improvement of Force Modulation Mode with Scanning Probe Microscopy for Imaging Viscoelasticity of Living Cells, Jpn. J. Appl. Phys., 41, 4952-4955 (2002).<\/li><li>T. Nitta, H. Haga, and K. Kawabata: Time Dependent Static Friction Force of Agar Gel-on-Glass Plate Immersed in Water, J. Phys. IV, 12, 319-320 (2002).<\/li><li>\u5ddd\u7aef \u548c\u91cd, \u4f50\u6238 \u5eb7\u6d0b, \u6c38\u5c71 \u660c\u53f2, \u82b3\u8cc0 \u6c38: \u30cf\u30a4\u30d6\u30ea\u30c3\u30c8\u8d70\u67fb\u578b\u30d7\u30ed\u30fc\u30d6\u9855\u5fae\u93e1\u306b\u3088\u308b\u751f\u7d30\u80de\u306e\u529b\u5b66\u7684\u89b3\u5bdf, \u300e\u5149\u5b66 (Jpn. J. Optics) \u300f 31\u5dfb\u30016\u53f7 483-488 (2002).<\/li><\/ul><h3>2001\u5e74<\/h3><ul><li>K. Kawabata, M. Nagayama, H. Haga, and T. Sambongi: Mechanical Effects on Collective Phenomena of Biological Systems: Cell Locomotion, Curr. Appl. Phys., 1, 66-71 (2001).<\/li><li>M. Nagayama, H. Haga, and K. Kawabata: Drastic Change of Local Stiffness Distribution Correlating to Cell Migration in Living Fibroblasts, Cell Motil. Cytoskeleton, 50, 173-179 (2001).<\/li><li>T. Saitoh, S. Takemura, K. Ueda, H. Hosoya, M. Nagayama, H. Haga, K. Kawabata, A. Yamagishi, and M. Takahashi: Differential Localization of Non-muscle Myosin II Isoforms and Phosphorylated Regulatory Light Chains in Human MRC-5 Fibroblasts, FEBS Letters, 509, 365-369 (2001).<\/li><\/ul><h3>2000\u5e74<\/h3><ul><li>H. Haga, S. Sasaki, K. Kawabata, E. Ito, T. Ushiki, and T. Sambongi: Elasticity Mapping of Living Fibroblasts by AFM and Immunofluorescence Observation of Cytoskeleton, Ultramicroscopy, 82, 253-258 (2000).<\/li><li>T. Nitta, H. Haga, K. Kawabata, K. Abe, and T. Sambongi: Comparing Microscopic with Macroscopic Elastic Properties of Polymer Gel, Ultramicroscopy, 82, 223-226 (2000).<\/li><li>H. Shiga, Y. Yamane, E. Ito, K. Abe, K. Kawabata, and H. Haga: Mechanical Properties of Membrane Surface of Cultured Astrocyte Revealed by Atomic Force Microscopy, Jpn. J. Appl. Phys., 39, 3711-3716 (2000).<\/li><li>K. Kawabata, H. Haga, T. Nitta, Y. Endo, M. Nagayama, E. Ito, and T. Sambongi: Big Softer Hole on Living Cell: Elasticity Imaging with AFM, Scanning and Force Microscopies for Biomedical Applications II, Proceedings of SPIE, 3922, 91-98 (2000).<\/li><li>Y. Yamane, H. Shiga, H. Haga, K. Kawabata, K. Abe, and E. Ito: Quantitative Analyses of Topography and Elasticity of Living and Fixed Astrocytes, J. Electron. Microsc., 49, 463-471 (2000).<\/li><li>H. Haga, M. Nagayama, K. Kawabata, E. Ito, T. Ushiki, and T. Sambongi: Time-Lapse Viscoelastic Imaging of Living Fibroblasts Using Force Modulation Mode in AFM, J. Electron. Microsc., 49, 473-481 (2000).<\/li><li>T. Tojima, Y. Yamane, H. Takagi, T. Takeshita, T. Sugiyama, H. Haga, K. Kawabata, T. Ushiki, K. Abe, T. Yoshioka, and E. Ito: Three-dimensional characterization of interior structures of exocytotic apertures of nerve cells using atomic force microscopy, Neuroscience, 101, 471-481 (2000).<\/li><li>\u82b3\u8cc0 \u6c38\u3001\u5ddd\u7aef \u548c\u91cd: \u7d30\u80de\u904b\u52d5\u306b\u4f34\u3046\u529b\u5b66\u69cb\u9020\u306eAFM\u7c98\u5f3e\u6027\u6e2c\u5b9a, \u300e\u96fb\u5b50\u9855\u5fae\u93e1\u300f 35\u5dfb\u30013\u53f7 276-278 (2000).<\/li><\/ul><h3>1999\u5e74<\/h3><ul><li>Y. Yamane, D. Hatakeyama, H. Haga, K. Abe, and E. Ito: Structures of Cultured Type 2 Astrocytes Revealed by Atomic Force Microscopy, Zoological Science, 16, 1-7 (1999).<\/li><li>\u5ddd\u7aef \u548c\u91cd\u3001\u82b3\u8cc0 \u6c38: \u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u3092\u3082\u3061\u3044\u305f\u57f9\u990a\u7d30\u80de\u306e\u7c98\u5f3e\u6027\u6e2c\u5b9a, \u300e\u751f\u7269\u7269\u7406\u300f 39\u5dfb\u30013\u53f7 179-181 (1999).<\/li><li>H. Haga, S. Sasaki, K. Kawabata, E. Ito, K. Abe, and T. Sambongi: Spatial and Temporal Viscoelastic Imaging of Living Fibroblasts by Atomic Force Microscopy, Biological Physics: Third International Syposium, CP 487, 229-234 (1999).<\/li><li>K. Kawabata, M. Morimoto, H. Ishizuka, T. Nitta, H. Haga, E. Ito, K. Abe, T. Ushiki, and T. Sambongi: Time Dependent Viscoelastic Image of Living Nerve Cells Using AFM, Biological Physics: Third International Syposium, CP 487, 235-239 (1999).<\/li><li>Y. Yamane, H. Shiga, H. Asou, H. Haga, K. Kawabata, K. Abe, and E. Ito: Dynamics of Adhesion of Astrocytes Analyzed by a Combination of Atomic Force Microscopy and Immunocytochemistry, Arch. Histol. Cytol., 62, 355-361 (1999).<\/li><li>P. Gorria, P. Barois, H. T. Nguyen, G. Sigaud, L. Navailles, C. W. Garland, and H. Haga: Thermal and Structural Study Close to a SmecticA-SmecticA Critical Point, Molecular Crystals &amp; Liquid Crystals 330, 1419-1426 (1999).<\/li><li>T. Hosono, M. Yamanaka, T. Tojima, Y. Yamane, H. Sadamoto, D. Hatakeyama, H. Haga, K. Kawabata, K. Abe, and E. Ito: Atomic Force Microscopic Observation of Three-Dimensional Morphological Changes of Neurons when Stimulated by a Neurotransmitter, Jpn. J. Appl. Phys., 38, 3940-3945 (1999).<\/li><li>\u5ddd\u7aef \u548c\u91cd\u3001\u82b3\u8cc0 \u6c38\u3001\u4e09\u672c\u6728 \u5b5d: \u539f\u5b50\u9593\u529b\u9855\u5fae\u93e1\u306b\u3088\u308b\u751f\u304d\u305f\u7d30\u80de\u306e\u7c98\u5f3e\u6027\u30de\u30c3\u30d4\u30f3\u30b0, \u300e\u65e5\u672c\u30d0\u30a4\u30aa\u30ec\u30aa\u30ed\u30b8\u30fc\u5b66\u4f1a\u8a8c\u300f 13\u5dfb\u30013\u53f7 1-9 (1999).<\/li><\/ul><h3>1998\u5e74<\/h3><ul><li>H. Haga and C. W. Garland: Calorimetric study of the smectic-A\uff0dhexatic-B transition in 3(10)OBC, Phys. Rev., E57, 603-609 (1998).<\/li><li>S. Sasaki, M. Morimoto, H. Haga, K. Kawabata, E. Ito, T. Ushiki, K. Abe, and T. Sambongi: Elastic Properties of Living Fibroblasts as Imaged Using Force Modulation Mode in Atomic Force Microscopy, Arch. Histol. Cytol., 61, 57-63 (1998).<\/li><li>H. Haga, S. Sasaki, M. Morimoto, K. Kawabata, E. Ito, K. Abe, and T. Sambongi: Imaging Elastic Properties of Soft Materials Immersed in Water Using Force Modulation Mode in Atomic Force Microscopy, Jpn. J. Appl. Phys., 37, 3860-3863 (1998).<\/li><\/ul><h3>1997\u5e74<\/h3><ul><li>H. Haga and C. W. Garland: Calorimetric Study of Heptyloxybenzylidene Butylaniline in Silica Aerogels, Liquid Crystals, 22, 275-277 (1997).<\/li><li>H. Haga, Z. Kutnjak, G. S. Iannacchione, S. Qian, D. Finotello, and C. W. Garland: Quasicritical Heat Capacity at a Smectic-A\uff0dHexatic-B Phase Transition, Phys. Rev., E56, 1808-1818 (1997).<\/li><li>H. Haga and C. W. Garland: Effect of Silica Aerosil Particles on Liquid Crystal Phase Transition, Phys. Rev., E56, 3044-3052 (1997).<\/li><li>F. Beaubois, T. Claverie, J. P. Marcerou, J. C. Rouillon, H. T. Nguyen, C. W. Garland, and H. Haga: Influence of Nematic Range on Birefringence, Heat Capacity, and Elastic Modulus near a Nematic\uff0dSmectic-A Phase Transition, Phys. Rev., E56, 5566-5574 (1997).<\/li><li>H. Haga and C. W. Garland: Thermal Study of the Influence of Aerosils on the Phase Transitions of Heptyloxybenzylidene Butylaniline, Liquid Crystals, 23, 645-652 (1997).<\/li><\/ul><h3>1996\u5e74<\/h3><ul><li>N. Noda, H. Haga, R. Nozaki, and Y. Shiozaki: A Calorimetric Study of [Rochelle Salt](1-x)-[Ammonium Rochelle Salt](x) Mixed Crystal System, Ferroelectrics, 184, 293-296 (1996).<\/li><li>\u82b3\u8cc0 \u6c38\u3001\u6c5f\u9593 \u5065\u53f8: Rb2ZnCl4\u7cfb\u5f37\u8a98\u96fb\u4f53\u306e\u6b63\u5e38\uff0d\u4e0d\u6574\u5408\u76f8\u8ee2\u79fb\u306b\u304a\u3051\u308b\uff13\u6b21\u5143\uff38\uff39\u7684\u81e8\u754c\u71b1\u7570\u5e38, \u300e\u56fa\u4f53\u7269\u7406\u300f 31\u5dfb\u30018\u53f7 687-695 (1996).<\/li><li>N. Noda, H. Nakano, H. Haga, R. Nozaki, and Y. Shiozaki: Evaluation of the Specific Heat Anomaly of RS(1-x)-ARS(x), J. Korean Phys. Soc., 29, S513-S516 (1996).<\/li><li>R. Nozaki, H. Nakano, N. Noda, H. Haga, and Y. Shiozaki: A Study of Dynamic Heat Capacity with AC Calorimetry, J. Korean Phys. Soc., 29, S736-S739 (1996).<\/li><\/ul><h3>1995\u5e74<\/h3><ul><li>N. Noda, H. Haga, T. Kikuta, R. Nozaki, and Y.Shiozaki: A Calorimetric Study of RS(1-x)-ARS(x) Mixedcrystalsystem(0.9&lt;=x&lt;=1.0), Ferroelectrics, 168, 169-175 (1995).<\/li><li>H. Haga, A. Onodera, Y. Shiozaki, K. Ema, and H. Sakata: Three-Dimensional XY Critical Behavior of Heat Capacity at Normal-Incommensurate Phase Transition in Rb2ZnCl4, J. Phys. Soc. Japan, 64 (3), 822-829 (1995).<\/li><li>H. Haga, R. Nozaki, Y. Shiozaki, and K. Ema: Preasymptotic 3D XY Critical Behavior of Heat Capacity at Normal Incommensurate Phase Transition in K2ZnCl4 and K2SeO4, J. Phys. Soc. Japan, 64 (11), 4258-4264 (1995).<\/li><\/ul><h3>1994\u5e74<\/h3><ul><li>A. Onodera, H. Haga, F. Denoyer, J. Godart, and Y. Shiozaki: Specific Heat and Critical Behavior in Thiourea at Normal-INC Phase Transition, Ferroelectrics, 155, 305-310 (1994).<\/li><li>H. Haga, A. Onodera, H. Yamashita, and Y. Shiozaki: Thermal and Dielectric Studies on Ferroelectric (CH3NHCH2COOH)3CaCl2 (TSCC), Ferroelectrics, 159, 55-60 (1994).<\/li><li>A. Onodera, O. Watanabe, H. Yamashita, H. Haga, and Y. Shiozaki: Kinetic Evolution in the Incommensurate Phase in K2ZnCl4, Ferroelectrics, 155, 299-304 (1994).<\/li><li>A. Onodera, O. Watanabe, H. Yamashita, H. Haga, and Y. Shiozaki: Dielectric Behavior and Relaxation Process in Modulated Phases in Thiourea, Ferroelectrics, 155, 311-316 (1994).<\/li><\/ul><h3>1993\u5e74<\/h3><ul><li>H. Haga, A. Onodera, M. Tokunaga, and Y. Shiozaki: Critical Behaviour of Specific Heat in Ferroelectric K2ZnCl4 and (NH4)2BeF4 at Normal-Incommensurate Phase Transition, J. Phys. Soc. Japan, 62 (5), 1597-1602 (1993).<\/li><li>H. Haga, A. Onodera, H. Yamashita, and Y. Shiozaki: New phase Transition in Ferroelectric (CH3NHCH2COOH)3CaCl2 at Low Temperatures, J. Phys. Soc. Japan, 62 (6), 1857-1859 (1993).<\/li><li>A. Onodera, B. A. Strukov, A. A. Belov, S. A. Taraskin, H. Haga, H. Yamashita, and Y. Uesu: Thermal and Dielectric Properties of a New Ferroelectric LaBGeO5, J. Phys. Soc. Japan, 62 (12), 4311-4315 (1993).<\/li><\/ul><h3>1992\u5e74<\/h3><ul><li>H. Haga, A. Onodera, and Y. Shiozaki: Specific Heat and Critical Indices Associated with Normal-Incommensurate Phase Transition in K2ZnCl4 and (NH4)2BeF4, Ferroelectrics, 125, 123-128 (1992).<\/li><li>A. Onodera, O. Watanabe, H. Haga, T. Kikuta, E. Suzuki, H. Yamashita, and Y. Shiozaki: Dielectric Properties and Phase Transition in Cesium Tetrachlorozincate Cs2ZnCl4, Ferroelectrics, 125, 141-146 (1992).<\/li><\/ul>","protected":false},"excerpt":{"rendered":"\u5317\u6d77\u9053\u5927\u5b66 \u5927\u5b66\u9662\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\uff08\u6559\u6388\uff09\u82b3\u8cc0 \u6c38\u3000\u306f\u304c\u3000\u3072\u3055\u3057English Page\u5ea7\u53f3\u306e\u9298\u3000\u300c\u865a\u5fc3\u5766\u61d0\u300d\u7d4c\u6b74\u662d\u548c42\u5e74 \u5317\u6d77\u9053\u4e0a\u5ddd\u90e1\u5263\u6df5\u753a\u751f\u307e\u308c\u662d\u548c60\u5e74 \u65ed\u5ddd\u6771\u9ad8\u7b49\u5b66\u6821\u5352\u696d\u5e73\u6210 1\u5e74 \u5317\u6d77\u9053\u5927\u5b66\u7406\u5b66\u90e8\u7269\u7406\u5b66\u79d1\u5352 &#8230;","protected":false},"author":1,"featured_media":0,"parent":579,"menu_order":410,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-1043","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/1043","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/comments?post=1043"}],"version-history":[{"count":109,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/1043\/revisions"}],"predecessor-version":[{"id":3069,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/1043\/revisions\/3069"}],"up":[{"embeddable":true,"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/pages\/579"}],"wp:attachment":[{"href":"https:\/\/altair.sci.hokudai.ac.jp\/g3\/wp-json\/wp\/v2\/media?parent=1043"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}