過去8年間に発表した主な研究論文をご紹介します。
2022年
- Y. Kumagai, J. Nio-Kobayashi, S. Ishihara, A. Enomoto, M. Akiyama, R. Ichihara, and H. Haga: The interferon-β/STAT1 axis drives the collective invasion of skin squamous cell carcinoma with sealed intercellular spaces, Oncogenesis, 11, 27 (2022).
2021年
- H. Oyama, A. Nukuda, S. Ishihara, and H. Haga: Soft Surfaces Promote Astrocytic Differentiation of Mouse Embryonic Neural Stem Cells via Dephosphorylation of MRLC in the Absence of Serum, Scientific Reports, 11, 19574, 1-11 (2021).
2020年
- S. Ishida-Ishihara, M. Akiyama, K. Furusawa, I. Naguro, H. Ryuno, T. Sushida, S. Ishihara, and H. Haga: Osmotic Gradients Induce Stable Dome Morphogenesis on Extracellular Matrix, Journal of Cell Science, 133, jcs243865 (2020).
2019年
- Y. Kumagai, J. Nio-Kobayashi, S. Ishida-Ishihara, H. Tachibana, R. Omori, A. Enomoto, S. Ishihara, and H. Haga: The Intercellular Expression of Type-XVII Collagen, Laminin-332, and Integrin-β1 Promote Contact Following during the Collective Invasion of a Cancer Cell Population, Biochem. Biophys. Res. Commun., 514, 1115-1121 (2019).
2018年
- S. Ishihara, K. Aoki, T. Mizutani, M. Amano, S. Nishimura, and H. Haga: Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells, Cell Structure and Function, 43, 177-185 (2018).
- I. Koh, K. Furusawa, and H. Haga: Anisotropic Multi-channel Collagen Gel (MCCG) Guides the Growth Direction of the Neurite-like Processes of PC12 Cells, Scientific Reports, 8, 13901, 1-10 (2018).
- H. Oyama, K. Takahashi, Y. Tanaka, H. Takemoto, and H. Haga: Long-term Culture of Human iPS Cell-derived Telencephalic Neuron Aggregates on Collagen Gel, Cell Structure and Function, 43, 85-94 (2018).
2017年
- M. Akiyama, T. Sushida, S. Ishida, and H. Haga: Conformational Mathematical Model of Collective Cell Migrations Based on Cell Polarity, Dev. Growth Differ., 59, 471-490 (2017).
2016年
- A. Nukuda, H. Endoh, M. Yasuda, T. Mizutani, K. Kawabata, and H. Haga: Role of ATF5 in the Invasive Potential of Diverse Human Cancer Cell Lines, Biochem. Biophys. Res. Commun., 474, 509–514 (2016).
- T. Mizutani, H. Haga, and K. Kawabata: Data Set for Comparison of Cellular Dynamics between Human AAVS1 Locus-modified and Wild-type Cells, Data in Brief, 6, 793–798 (2016).
- S. Ishihara, T. Mizutani, K. Kawabata, and H. Haga: An Improved Method for Western Blotting When Extracting Proteins from Mammalian Cells Cultured on a Collagen Gel under Serum-free Conditions, Cytotechnology, 68, 25-32 (2016).
2015年
- M. Imai, K. Furusawa, T. Mizutani, K. Kawabata, and H. Haga: Three-dimensional morphogenesis of MDCK cells induced by cellular contractile forces on a viscous substrate, Scientific Reports, 5, 14208, 1-10 (2015).
- T. Mizutani, R. Li, H. Haga, and K. Kawabata: Transgene Integration into the Human AAVS1 Locus Enhances Myosin II-Dependent Contractile Force by Reducing Expression of Myosin Binding Subunit 85, Biochem. Biophys. Res. Commun., 465, 270-274 (2015).
- A. Nukuda, C. Sasaki, S. Ishihara, T. Mizutani, K. Nakamura, T. Ayabe, K. Kawabata, and Hisashi Haga: Stiff Substrates Increase YAP-Signaling-Mediated Matrix Metalloproteinase-7 Expression, Oncogenesis, 4, e165 (2015).
- Y. Iguchi, S. Ishihara, Y. Uchida, K. Tajima, T. Mizutani, K. Kawabata, and H. Haga: Filamin B enhances the invasiveness of cancer cells into 3D collagen matrices, Cell Structure and Function, 40, 61-67 (2015).
- K. Takemoto, S. Ishihara, T. Mizutani, K. Kawabata, and H. Haga: Compressive Stress Induces Dephosphorylation of the Myosin Regulatory Light Chain via RhoA Phosphorylation by the Adenylyl Cyclase/Protein Kinase A Signaling Pathway, PLOS ONE, 10, e0117937 (2015).
- S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, and H. Haga: Activating Transcription Factor 5 Enhances Radioresistance and Malignancy in Cancer Cells, Oncotarget, 6, 4602-4614 (2015).
- N. Yamaguchi, T. Mizutani, K. Kawabata, and H. Haga: Leader Cells Regulate Collective Cell Migration via Rac Activation in the Downstream Signaling of Integrin Beta1 and PI3K, Scientific Reports, 5, 7656, 1-8 (2015).