ポストゲノムタンパク質解析イノベーションハブ:2010年度

  1.  Kobashigawa Y., Harada K., Yoshida N., Ogura K., Inagaki F.
    Phosphoinositide-incorporated lipid-protein Nanodiscs: A tool for studying protein-lipid interactions.
    Anal Biochem., 410, 77-83(2011)

  2. Watanabe Y., Noda NN., Kumeta H., Suzuki K., Ohsumi Y., Inagaki F.
    Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by ATG19 and ATG34.
    J Biol Chem., 285, 30026-30033( 2010)

  3. Yamaguchi M., Noda NN., Nakatogawa H., Kumeta H., Ohsumi Y., Inagaki F.
    Autophagy-related protein (Atg) 8-family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway.
    J Biol Chem., 285, 29599-29607(2010)

  4. Takahasi K., Horiuchi M., Fujii K., Nakamura S., Noda NN., Yoneyama M., Fujita T., Inagaki F.
    Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change.
    Genes Cells., 15, 901-910(2010)

  5. Ogura K., Kumeta H., Inagaki F.
    Structure determination of proteins in(2)H(2)O solution aided by a deuterium-decoupled 3D HCA(N)CO experiment.
    J Biomol NMR., 47, 243-248( 2010)

  6. Kumeta H., Watanabe M., Nakatogawa H., Ymaguchi M., Ogura K., Adachi W., Fujioka Y., Noda NN., Ohsumi Y., Inagaki F.
    The NMR structure of the autophagy-related protein Atg8.
    J Biomol NMR., 47, 237-241( 2010)

  7. Takaku T., Ogura K., Kumeta H., Yoshida N., Inagaki F.
    Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42.
    J. Biol. Chem., 285, 19346-19353( 2010)

  8. Saio T., Yokochi M., Kumeta H., Inagaki F.
    PCS-based structure determination of protein-protein complexes.
    J Biomol NMR., 46, 271-280( 2010)

  9. Fujii K., Nakamura S., Takahashi K., Inagaki F
    Systematic characterization by mass spectrometric analysis of phosphorylation sites in IRF-3 regulatory domain activated by IKK-i.
    J Proteomics., 73, 1196-1203( 2010)

  10. Hu S.-Q., Gao Y.-G., Tajima K., Sunagawa N., Zhou Y., Kawano S., Fujiwara T., Yoda T., Shimura D., Satoh Y., Munekata M., Tanaka I., Yao M.
    Structure of bacterial cellulose synthase subunit D octamer with four inner passageways.
    Proc. Natl. Acad. Sci. USA., 107, 17957-17961( 2010).

  11. Itou H., Watanabe N., Yao M., Shirakihara Y., Tanaka I.
    Crystal structures of the multidrug binding repressor Corynebacterium glutamicum CgmR in complex with inducers and with operator.
    J. Mol. Biol., 403, 174-184( 2010).

  12. Kitago Yu., Watanabe N., Tanaka I.
    Semi-automated protein crystal mounting device for the sulfur single-wavelength anomalous diffraction method.
    J. Appl. Cryst., 43, 341-346( 2010).

  13. Ogata D., Ooi T., Fujiwara T., Taguchi S., Tanaka I. Yao M.
    Crystallization and preliminary X-ray studies of azoreductases from Bacillus sp. B29.
    Acta Cryst., F66, 503-505( 2010).

  14. Nuemket N., Tanaka Y., Tsukamoto K., Tsuji T., Nakamura K., Kozaki S., Yao M., Tanaka I.
    Preliminary X-ray crystallographic study of the receptor binding domain of the D/C mosaic neurotoxin from Clostridium botulinum.
    Acta Cryst., F66, 608-610( 2010).

  15. Kouno T., Watanabe N., Sakai N., Nakamura T., Nabeshima Y., Morita M., Mizuguchi M., Aizawa T., Demura M., Imanaka T., Tanaka I., Kawano K.
    The Structure of Physarum polycephalum Hemagglutinin I Suggests a Minimal Carbohydrate Recognition Domain of
    Legume Lectin Fold.
    J. Mol. Biol., 405, 560-569( 2011).

  16. Matsuoka E., Tanaka Y., Kuroda M., Shouji Y., Ohta T., Tanaka I., Yao M.
    Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding.
    Protein Science., 20, 406-416( 2011).

  17. Tanaka Y., Hirano N., Kaneko J., Kamio Y., Yao M., Tanaka I.
    2-Methyl-2,4-pentanediol induces spontaneous assembly of staphylococcal α-hemolysin into heptameric pore structure.
    Protein Science., 20, 448-456( 2011).

  18. W. Wang, S. Itoh, T. Aizawa, K. Sakai, T. Ohkuma, M. Demura
    Development of an injectable chitosan/marine collagen composite gel
    Biomedical Materials, 5 065009( 2010).

  19. Y. Nonaka, H. Muto, T. Aizawa, E. Okabe, S. Myoba, T. Yokoyama, S. Saito, F. Tatami, Y. Kumaki, M. Kamiya, T. Kikukawa, M. Mizuguchi, S. Takiya, M. Kinjo, M. Demura, K. Kawano
    STPR, A 23-amino-acid tandem repeat domain, found in the human function-unknown protein ZNF821
    Biochemistry, 49, 8367-8375 (2010).

  20. M. Takahashi, M. Mizuguchi, H. Shinoda, T. Aizawa, M.Demura, H. Okazawa, K. Kawano
    Polyglutamine tract-binding protein-1 binds to U5-15kD via a continuous 23-residue segment of the C-terminal domain.
    Biochim. Biophys. Acta – Proteins and Proteomics, 1804,1500-1507( 2010).

  21. M. Kamiya, K. Oyauchi, Y. Sato, T. Yokoyama, M. Wang, T. Aizawa, Y. Kumaki, M. Mizuguchi, K. Imai, M. Demura, K. Suzuki, K. Kawano
    Structure-activity relationship of a novel pentapeptide with cancer cell growth-inhibitory activity.
    J.Peptide Sci., 16, 242-248( 2010).

  22. J. Tamogami, T. Kikukawa, Y. Ikeda, A. Takemura, M. Demura,,N. Kamo
    The photochemical reaction cycle and photo-induced proton transfer of sensory rhodopsin II (phoborhodopsin) from Halobacterium salinarum
    Biophys. J., 98, 1353-1363( 2010).[Selected as Featured Article; available for free.]

  23. Kawaguchi A., Suzuki T., Kimura T., Sakai N., Ayabe T., Sawa H., Hasegawa H.
    Functional analysis of an alpha-helical antimicrobial peptide derived from a novel mouse defensin-like gene
    Biochem. Biophys. Res. Commun. 3984), 778-784(2010).

  24. Masuda K, Sakai N, Nakamura K, Yoshioka S, Ayabe T.
    Bactericidal activity of mouse α-defensin cryptdin-4 predominantly affects non-commensal bacteria
    J. Innate Immun. Published Online: November 22, 2010

  25. Ui M., Tanaka Y., Tsumuraya T., Fujii I., Inoue M., Hirama M., and Tsumoto K.
    Structural and Energetic Hot-Spots for the Interaction between a Ladder-like Polycyclic Ether and the Anti-
    Ciguatoxin Antibody
    Molecular BioSystems, 7, 793-798( 2011)

  26. Morikawa K., Ohniwa R., Ohta T., Tanaka Y., Takeyasu K., and Msadek T.
    Adaptation beyond the Stress Response: Cell Structure Dynamics and Population Heterogeneity in Staphylococcus aureus.
    Microbes and Environments , 25, 75-82( 2010)

  27. Nagatoishi S., Tanaka Y., Kudou M., and Tsumoto K.
    Temperature and salt concentration alter base-sequence selectivity of a duplex DNA-binding protein
    Mol. Biosyst., 6, 98-101( 2010)

  1. 稲垣冬彦
    北大薬学部退任を迎えるに当たって
    薬学雑誌, 130, 1251-1262( 2010)

  2. 田中 勲
    2009年度ノーベル化学賞「翻訳装置リボソームの構造解析」をめぐって
    Isotope News, 672, 16-17( 2010).

  3. 渡邉信久,田中 勲
    新しいX線結晶構造解析技術( New Technique for X-ray Crystal Structure Analysis of Proteins)
    BIO INDUSTRY, 283), 50-54( 2011).

  (招待講演)

  1. August 2010
    Cairns, Australia
    International Conference on Magnetic Resonance in Biological Systems
    Structural biology of selective autophagy.
    Inagaki F.

  2. October 2010
    Xian, Shaanxi
    Sino-Japan Symposium on Autopyagy
    Structural biology of autophagy
    Inagaki F.

  3. October 2010
    Xian, Shaanxi
    Sino-Japan Symposium on Autopyagy
    Structural basis of selective autophagy
    Nobuo N.Noda.

  4. December 2010
    Hawaii, USA
    2010 International Chemical Congress of Pacific Basin Societies
    NMR studies of molecular interaction using PCS and nanodisc
    Inagaki F.

  5. December 2010
    Hawaii, USA
    2010 International Chemical Congress of Pacific Basin  Societies
    Structural biology of autophagy
    Inagaki F.

  6. March 2011
    Osaka, Japan
    Towards Comprehensive Understanding of Immun Dynamism (TCUID2011)
    Structural biology of TIR domains
    Inagaki F.

  7. November 2010
    Suita, JAPAN
    CCP4 workshop on Computational Crystallography
    LAFIRE: Automated refinement program for protein crystallography
    Yao M.

    (口頭発表)

  8. March 2011
    Sapporo, JAPAN
    International Fusion-Bioscience Symposium for young researchers
    The Recognition Mechanism of eIF2β-NTD for its partner proteins eIF5 and eIF2Bε-CTD
    Gai Z.-Q., Kitagawa Y., Ose T., Tanaka Y., Yao M., Tanaka I.

  9. Jul-10
    Sapporo, JAPAN
    Preparing Future Faculty: An Introduction to Teaching and Writing for Graduate Students, Symposium: A Roadmap to International Career Development
    Career Development Program for Hokkaido University Graduate Students
    Demura, M

  1. 2010年7月
    阿蘇市
    第34回阿蘇シンポジウム 感染症と免疫の構造生物学
    インターフェロン産生系の構造生物学
    稲垣冬彦

  2. 2010年7月
    吹田市
    大阪大学蛋白質研究所セミナー 超高磁場が拓く生態系NMR:最新技術と応用
    北大におけるNMR研究のための技術開発
    稲垣冬彦

  3. 2010年10月
    吹田市 
    蛋白研セミナー・包括脳ネットワーク神経細胞プロテオミクス研究会「神経科学と構造生物学の融合」
    シグナル伝達ドメインの構造生物学
    稲垣冬彦

  4. 2010年11月
    札幌市
    第4回形態科学シンポウム
    オートファジーの構造生物学
    稲垣冬彦

  5. 2010年6月
    札幌市
    第10回日本蛋白質学会年会 ノーベル賞特別シンポジウム
    リボソームの翻訳因子作用中心に位置する動的タンパク質複合体
    内海利男,長沼孝雄,野村直子,望月正弘,馬場健太朗,姚 閔,田中 勲

  6. 2010年6月
    札幌市
    第10回日本蛋白質学会年会
    自動精密化プログラムLAFIREの展開-核酸そして創薬へ
    姚 閔,周 勇,山下恵太郎,田中 勲

  7. 2010年12月
    札幌市
    セルロース学会北海道・東北支部セミナー「セルロースの生合成と分解」
    X線結晶構造解析によるバクテリアセルロース合成機構の研究
    姚 閔

  8. 2011年3月
    水戸市
    第19回 生体分子科学コロキウム
    構造生物学研究における予期せぬ発見
    田中良和

なし